SCHEMBL15213593

SCHEMBL15213593

c1ccc(-c2ccc(N(c3ccc4c(c3)-c3ccccc3C43c4ccccc4-c4ccccc43)c3ccc4c(c3)C3(c5ccccc5-c5ccccc53)c3ccccc3-4)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 15/20 0.40
MAPT P10636 3/20 0.34
KDM4E B2RXH2 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
ALDH1A1 P00352 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
MEN1 O00255 2/20 0.34
LMNA P02545 2/20 0.34
KMT2A Q03164 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
OPRK1 P41145 1/20 0.34
THRB P10828 2/20 0.33
APAF1 O14727 1/20 0.33
NPC1 O15118 1/20 0.33
XBP1 P17861 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25563537 0.98 PDK2 (0.39) PDK2MAPTKDM4EL3MBTL1TDP1
SCHEMBL25563603 0.98 PDK2 (0.39) PDK2MAPTKDM4EL3MBTL1TDP1
SCHEMBL24647042 0.98 PDK2 (0.39) PDK2MAPTKDM4EL3MBTL1TDP1
SCHEMBL24750437 0.98 PDK2 (0.39) PDK2MAPTKDM4EL3MBTL1TDP1
SCHEMBL19001968 0.97 PDK2 (0.41) PDK2MAPTKDM4EL3MBTL1TDP1
SCHEMBL14597173 0.97 PDK2 (0.37) PDK2MAPTKDM4EL3MBTL1TDP1
SCHEMBL24646537 0.96 PDK2 (0.38) PDK2MAPTKDM4EL3MBTL1TDP1
SCHEMBL17854678 0.96 PDK2 (0.43) PDK2MAPTKDM4EL3MBTL1TDP1
SCHEMBL23666556 0.95 PDK2 (0.46) PDK2MAPTL3MBTL1MEN1LMNA
SCHEMBL19533803 0.95 PDK2 (0.46) PDK2MAPTL3MBTL1MEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023117836-A1 ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-06-29 WO disclosed
US-20230210002-A1 COMPOSITION, AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-29 US disclosed
US-20230210002-A1 COMPOSITION, AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-29 US disclosed
US-20220310930-A1 ORGANIC ELECTROLUMINESCENT ELEMENT EMITTING LIGHT AT HIGH LUMINOUS EFFICIENCY AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2022-09-29 US disclosed
US-11387414-B2 Spirobifluorene compounds for organic electroluminescent devices MERCK PATENT GMBH (DE) 2022-07-12 US disclosed
US-20220059775-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS USING THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2022-02-24 US disclosed
US-20210328156-A1 MIXTURE, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO.,LTD. (JP) 2021-10-21 US disclosed
US-20210296591-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPLIANCE USING THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2021-09-23 US disclosed
US-11069861-B2 Mixture, organic electroluminescence device and electronic equipment IDEMITSU KOSAN CO., LTD. (JP) 2021-07-20 US disclosed
US-10944056-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2021-03-09 US disclosed
US-9812648-B2 Spirobifluorene compounds for organic electroluminescent devices MERCK PATENT GMBH (DE) 2017-11-07 US disclosed
EP-3235892-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmbH (DE) 2017-10-25 EP disclosed
WO-2017123008-A1 ORGANIC LIGHT-EMITTING DEVICE, ORGANIC LIGHT-EMITTING DISPLAY DEVICE, AND COMPOUND FOR ORGANIC LIGHT-EMITTING DEVICE 덕산네오룩스 주식회사 2017-07-20 WO disclosed
EP-2814906-B1 SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2016-10-19 EP disclosed
US-20160111644-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-21 US disclosed
US-20160111644-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-21 US disclosed
EP-3010066-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2016-04-20 EP disclosed
US-20150065730-A1 SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2015-03-05 US disclosed
US-20150065730-A1 SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2015-03-05 US disclosed
WO-2013120577-A1 SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2013-08-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11387414-B2 Spirobifluorene compounds for organic electroluminescent devices PKD1, PIEZO1, AQP1 PDK2 233/4885MAPT 2733/4885KDM4E 4609/4885
US-10944056-B2 Materials for organic electroluminescent devices PIEZO1, TMEM109, EPN1 PDK2 448/4885MAPT 2692/4885KDM4E 4050/4885
US-20210296591-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPLIANCE USING THE SAME OLA1, AOC1, ODC1 PDK2 1237/4885MAPT 2539/4885KDM4E 1043/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.