SCHEMBL15213622

SCHEMBL15213622

c1ccc(-c2ccc3c(c2)Oc2cc(-c4ccccc4)ccc2N3c2cccc3c2C2(c4ccccc4-c4ccccc42)c2ccccc2-3)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 8/20 0.37
PDE6D O43924 1/20 0.33
HTR1A P08908 1/20 0.32
DRD2 P14416 1/20 0.32
CA12 O43570 1/20 0.31
CA9 Q16790 1/20 0.31
PTGS2 P35354 1/20 0.31
TYMS P04818 1/20 0.31
PTPRC P08575 1/20 0.31
MEN1 O00255 2/20 0.30
NPC1 O15118 2/20 0.30
MAPT P10636 2/20 0.30
RAB9A P51151 2/20 0.30
KMT2A Q03164 2/20 0.30
SMN1; SMN2 Q16637 2/20 0.30
L3MBTL1 Q9Y468 2/20 0.30
APAF1 O14727 1/20 0.30
LMNA P02545 1/20 0.30
THRB P10828 1/20 0.30
XBP1 P17861 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15213625 0.87 PDK2 (0.35) PDK2PDE6DTYMS
SCHEMBL17816798 0.86 PDK2 (0.35) PDK2PDE6DTYMSMEN1NPC1
SCHEMBL15213620 0.83 PDK2 (0.36) PDK2PDE6DTYMS
SCHEMBL25495732 0.83 PDK2 (0.39) PDK2PDE6DTYMSMEN1MAPT
SCHEMBL15213617 0.83 PDK2 (0.39) PDK2PDE6DTYMSMEN1KMT2A
SCHEMBL25495733 0.82 P2RX4 (0.36) PDK2MEN1NPC1MAPTRAB9A
SCHEMBL16858149 0.82 PDE6D (0.33) PDK2PDE6DTYMSMEN1MAPT
SCHEMBL25495719 0.82 PDK2 (0.38) PDK2PDE6DTYMSMEN1KMT2A
SCHEMBL25495737 0.80 PDE6D (0.44) PDK2PDE6DMEN1MAPTKMT2A
SCHEMBL16544726 0.80 PDK2 (0.36) PDK2PDE6DMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023117836-A1 ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-06-29 WO disclosed
US-20230159434-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-25 US disclosed
US-20230159434-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-25 US disclosed
US-11387414-B2 Spirobifluorene compounds for organic electroluminescent devices MERCK PATENT GMBH (DE) 2022-07-12 US disclosed
US-20210336144-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-10-28 US disclosed
US-11018304-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2021-05-25 US disclosed
US-10944056-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2021-03-09 US disclosed
US-20200259086-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2020-08-13 US disclosed
US-20200235305-A1 SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-07-23 US disclosed
US-10665789-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-05-26 US disclosed
EP-3235892-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmbH (DE) 2017-10-25 EP disclosed
US-20170155050-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-01 US disclosed
US-20170155050-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-01 US disclosed
EP-3101088-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmbH (DE) 2016-12-07 EP disclosed
EP-2814906-B1 SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2016-10-19 EP disclosed
US-20160260901-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-09-08 US disclosed
US-20160260901-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-09-08 US disclosed
US-20150065730-A1 SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2015-03-05 US disclosed
US-20150065730-A1 SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2015-03-05 US disclosed
WO-2013120577-A1 SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2013-08-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11387414-B2 Spirobifluorene compounds for organic electroluminescent devices PKD1, PIEZO1, AQP1 PDK2 233/4885PDE6D 1573/4885HTR1A 3046/4885
US-20200235305-A1 SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES PKD1, PIEZO1, AQP1 PDK2 283/4885PDE6D 1390/4885HTR1A 2976/4885
US-20230159434-A1 MATERIALS FOR ELECTRONIC DEVICES OCIAD2, AOC2, OCIAD1 PDK2 741/4885PDE6D 1917/4885HTR1A 1069/4885
US-10944056-B2 Materials for organic electroluminescent devices PIEZO1, TMEM109, EPN1 PDK2 448/4885PDE6D 1786/4885HTR1A 2897/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.