Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2471288 | 0.82 | MAPT (0.48) | GAALMNATSHRHTTTDP1 | |
| SCHEMBL9311840 | 0.81 | ALDH1A1 (0.36) | AKR1B1LMNATSHRCES2CES1 | |
| SCHEMBL2209032 | 0.81 | CA2 (0.38) | TSHRHTTTDP1KDM4EALDH1A1 | |
| SCHEMBL7853008 | 0.80 | ALDH1A1 (0.33) | AKR1B1LMNATSHRHTTCES2 | |
| SCHEMBL1510129 | 0.79 | KEAP1 (0.52) | HTTFFAR1TDP1ALDH1A1MAPT | |
| SCHEMBL17503649 | 0.78 | — | — | |
| SCHEMBL27821299 | 0.78 | HDAC6 (0.52) | — | |
| SCHEMBL11284957 | 0.77 | CYP19A1 (0.50) | TDP1ALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL1443509 | 0.76 | CYP4F2 (0.41) | GAALMNATSHRKDM4EALDH1A1 | |
| SCHEMBL3540650 | 0.76 | HDAC3 (0.55) | HTTFFAR1ALDH1A1MAPTKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 330 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348694-A1 | SHELF LIFE- AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS | BASF SE (DE) | 2023-11-02 | — | — | US | claimed |
| CN-114746390-A | Storage and transport stabilizers for polymerizable compounds | 巴斯夫欧洲公司 | 2022-07-12 | — | — | CN | claimed |
| US-20210371417-A1 | AZAINDOLE COMPOUNDS AS HISTONE METHYLTRANSFERASE INHIBITORS | GLOBAL BLOOD THERAPEUTICS, INC. | 2021-12-02 | — | — | US | claimed |
| WO-2021105038-A1 | SHELF LIFE- AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS | BASF SE (DE) | 2021-06-03 | — | — | WO | claimed |
| US-20210052561-A1 | TARGETING ASPARTATE BETA-HYDROXYLASE SUPPRESSES TUMOR MALIGNANCY AND METASTASIS | MIDWESTERN UNIVERSITY | 2021-02-25 | — | — | US | claimed |
| EP-3634962-A1 | AZAINDOLE COMPOUNDS AS HISTONE METHYLTRANSFERASE INHIBITORS | Global Blood Therapeutics, Inc. (US) | 2020-04-15 | — | — | EP | claimed |
| CN-110997671-A | Azaindole compounds as histone methyltransferase inhibitors | 全球血液疗法股份有限公司 | 2020-04-10 | — | — | CN | claimed |
| US-20180354947-A1 | AZAINDOLE COMPOUNDS AS HISTONE METHYLTRANSFERASE INHIBITORS | GLOBAL BLOOD THERAPEUTICS, INC. | 2018-12-13 | — | — | US | claimed |
| WO-2018226998-A1 | AZAINDOLE COMPOUNDS AS HISTONE METHYLTRANSFERASE INHIBITORS | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2018-12-13 | — | — | WO | claimed |
| US-9701638-B2 | Therapeutic hydroxyquinolones | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-07-11 | — | — | US | claimed |
| US-5723480-A | Adhesion receptor antagonists III | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-03-03 | — | — | US | claimed |
| EP-0816439-A1 | Water-insoluble azo colouring agents derived from N-acetoacetyldehydrothiotoluidine | Clariant GmbH (DE) | 1998-01-07 | — | — | EP | claimed |
| US-5561148-A | Adhesion receptor antagonists III | MERCK PATENT GESELLSCHAFT MIT BESHRANKTER HAFTUNG (DE) | 1996-10-01 | — | — | US | claimed |
| US-5527476-A | RHODIUM CATALYST FOR CROSSLINKING METHYLHYDROGENSILOXANES IN TREATING FIBERS OR FABRICS | DOW CORNING CORPORATION (US) | 1996-06-18 | — | — | US | claimed |
| US-5409620-A | Fiber treatment compositions containing organofunctional siloxanes and methods for the preparation thereof | DOW CORNING CORPORATION (US) | 1995-04-25 | — | — | US | claimed |
| EP-0635263-A2 | Angiotensin (AII) antagonists as inhibitors of the growth of adipose tissue | AMERICAN CYANAMID COMPANY (US) | 1995-01-25 | — | — | EP | claimed |
| US-4598033-A | IMPROVED SENSITIVITY AND DURAVILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1986-07-01 | — | — | US | claimed |
| US-4412992-A | 2-Hydroxy-5-phenylazobenzoic acid derivatives and method of treating ulcerative colitis therewith | BIOREX LABORATORIES LIMITED (GB) | 1983-11-01 | — | — | US | claimed |
| US-4276295-A | VASODILATORS, HYPOTENSIVE, ANTIATHEROSCLEROTIC | Ishikawa, Masayuki (JP) | 1981-06-30 | — | — | US | claimed |
| US-4182897-A | ENZYME INHIBITORS FOR PROTEOLYTIC ENZYMES | TORII & CO., LTD. (JP) | 1980-01-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210371417-A1 | AZAINDOLE COMPOUNDS AS HISTONE METHYLTRANSFERASE INHIBITORS | EHMT2, EHMT1, EZH2 | AKR1B1 3088/4885GAA 203/4885PTGS1 4645/4885 |
| US-20180354947-A1 | AZAINDOLE COMPOUNDS AS HISTONE METHYLTRANSFERASE INHIBITORS | EHMT2, EHMT1, EZH2 | AKR1B1 3088/4885GAA 203/4885PTGS1 4645/4885 |
| US-20210052561-A1 | TARGETING ASPARTATE BETA-HYDROXYLASE SUPPRESSES TUMOR MALIGNANCY AND METASTASIS | ASPH, GOT1, FOLH1 | AKR1B1 93/4885GAA 309/4885PTGS1 958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.