Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 6/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 6/20 | 0.32 |
| ▸ | RAB9A | P51151 | 6/20 | 0.32 |
| ▸ | HTT | P42858 | 5/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.31 |
| ▸ | GALR3 | O60755 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12524569 | 0.93 | ALDH1A1 (0.41) | ALDH1A1CHRM1TP53MEN1KMT2A | |
| SCHEMBL13788680 | 0.87 | CHRM1 (0.31) | ALDH1A1CHRM1LMNAMAPK1MEN1 | |
| SCHEMBL4456152 | 0.82 | — | — | |
| SCHEMBL20465806 | 0.79 | TP53 (0.48) | ALDH1A1TP53LMNAMAPK1MEN1 | |
| SCHEMBL27458343 | 0.76 | TP53 (0.46) | ALDH1A1TP53LMNAMAPK1MEN1 | |
| SCHEMBL15868789 | 0.76 | MEN1 (0.34) | ALDH1A1CHRM1TP53LMNAMAPK1 | |
| SCHEMBL8386432 | 0.73 | TBXAS1 (0.67) | ALDH1A1LMNAMAPK1MEN1KMT2A | |
| SCHEMBL691481 | 0.73 | TP53 (0.48) | ALDH1A1TP53LMNAMAPK1POLB | |
| SCHEMBL28828285 | 0.72 | TP53 (0.39) | TP53MEN1KMT2A | |
| SCHEMBL250676 | 0.72 | NPC1 (0.56) | ALDH1A1TP53LMNAMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2687518-B1 | NITROGEN-CONTAINING SATURATED HETEROCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORP (JP) | 2017-11-01 | — | — | EP | disclosed |
| US-8835643-B2 | Molecules, compositions, and methods for light absorption | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2014-09-16 | — | — | US | disclosed |
| US-20140193348-A1 | MOLECULES, COMPOSITIONS, AND METHODS FOR LIGHT ABSORPTION | CRESTLINE DIRECT FINANCE, L.P. | 2014-07-10 | — | — | US | disclosed |
| WO-2013123658-A1 | AZOBENZENE COMPOUNDS WITH CHOLESTEROL GROUP AND THEIR SUNSCREEN COMPOSITIONS | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2013-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140193348-A1 | MOLECULES, COMPOSITIONS, AND METHODS FOR LIGHT ABSORPTION | CRY1, ERCC1, CRY2 | ALDH1A1 77/4885CHRM1 4616/4885TP53 233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.