Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 2/20 | 0.76 |
| ▸ | GNG2 | P59768 | 2/20 | 0.47 |
| ▸ | GNB1 | P62873 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10059473 | 0.86 | SOS1 (1.00) | SOS1GNG2GNB1PTPN7KDM4E | |
| SCHEMBL24274926 | 0.83 | GNG2 (0.54) | SOS1GNG2GNB1CA12CA9 | |
| SCHEMBL10175951 | 0.83 | SOS1 (0.72) | SOS1GNG2GNB1PTPN7KDM4E | |
| SCHEMBL10145463 | 0.83 | SOS1 (0.72) | SOS1GNG2GNB1PTPN7KDM4E | |
| SCHEMBL2737206 | 0.81 | SOS1 (0.85) | SOS1GNG2GNB1CA12CA9 | |
| SCHEMBL13648665 | 0.81 | SOS1 (0.76) | SOS1GNG2GNB1PTPN7KDM4E | |
| SCHEMBL10145570 | 0.80 | SOS1 (0.78) | SOS1GNG2GNB1CA9PTPN7 | |
| SCHEMBL2737169 | 0.78 | SOS1 (0.66) | SOS1GNG2GNB1KDM4EHPGD | |
| SCHEMBL13648666 | 0.78 | SOS1 (0.65) | SOS1GNG2GNB1PTPN7KDM4E | |
| SCHEMBL13648663 | 0.77 | SOS1 (0.67) | SOS1GNG2GNB1PTPN7HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9506929-B2 | Selective detection of amino group containing thiols | PORTLAND STATE UNIVERSITY (US) | 2016-11-29 | — | — | US | disclosed |
| US-9506929-B2 | Selective detection of amino group containing thiols | PORTLAND STATE UNIVERSITY (US) | 2016-11-29 | — | — | US | disclosed |
| US-20150010938-A1 | SELECTIVE DETECTION OF THIOLS | OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND STATE UNIVERSITY (US) | 2015-01-08 | — | — | US | disclosed |
| US-20150010938-A1 | SELECTIVE DETECTION OF THIOLS | OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND STATE UNIVERSITY (US) | 2015-01-08 | — | — | US | disclosed |
| WO-2013126816-A1 | SELECTIVE DETECTION OF THIOLS | OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND STATE UNIVERSITY (US) | 2013-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150010938-A1 | SELECTIVE DETECTION OF THIOLS | CBS, CTH, GSTM2 | SOS1 916/4885GNG2 404/4885GNB1 567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.