Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.69 |
| ▸ | PRNP | P04156 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.69 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | NQO2 | P16083 | 1/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SI | P14410 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2031645 | 0.83 | ALDH1A1 (0.71) | ALDH1A1KDM4ELMNAHPGDPRNP | |
| SCHEMBL3054179 | 0.83 | ALDH1A1 (0.70) | ALDH1A1KDM4ELMNAHPGDSLC9A1 | |
| SCHEMBL13078607 | 0.81 | SLC9A1 (0.59) | ALDH1A1KDM4ELMNAHPGDSLC9A1 | |
| SCHEMBL12885825 | 0.81 | ALDH1A1 (0.69) | ALDH1A1KDM4ELMNAHPGDPRNP | |
| SCHEMBL28201855 | 0.81 | SLC9A1 (0.59) | ALDH1A1KDM4ELMNAHPGDPRNP | |
| SCHEMBL7118702 | 0.81 | ALDH1A1 (0.69) | ALDH1A1KDM4ELMNAHPGDPRNP | |
| SCHEMBL4163540 | 0.81 | ALDH1A1 (0.68) | ALDH1A1KDM4ELMNAHPGDPRNP | |
| SCHEMBL6671019 | 0.80 | NR4A1 (0.74) | ALDH1A1KDM4ELMNAHPGDPRNP | |
| SCHEMBL4943738 | 0.79 | SLC9A1 (0.57) | ALDH1A1KDM4ELMNAHPGDPRNP | |
| SCHEMBL8420534 | 0.79 | SLC9A1 (0.56) | ALDH1A1KDM4ELMNAHPGDSLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100345847-C | Novel biarylcarboxamides | ASTRAZENECA AB (SE) | 2007-10-31 | — | — | CN | claimed |
| CN-1400973-A | Novel biarylcarboxamides | ASTRAZENECA AB (SE) | 2003-03-05 | — | — | CN | claimed |
| US-8871976-B2 | Chalcone structure fluorescence dye for embryonic stem cell probe | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2014-10-28 | — | — | US | disclosed |
| US-20130224790-A1 | Chalcone Structure Fluorescence Dye For Embryonic Stem Cell Probe | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2013-08-29 | — | — | US | disclosed |
| CN-100345847-C | Novel biarylcarboxamides | ASTRAZENECA AB (SE) | 2007-10-31 | — | — | CN | disclosed |
| CN-1400973-A | Novel biarylcarboxamides | ASTRAZENECA AB (SE) | 2003-03-05 | — | — | CN | disclosed |