Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | PRNP | P04156 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.69 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.58 |
| ▸ | FEN1 | P39748 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.54 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.54 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11826852 | 0.85 | ALDH1A1 (0.63) | ALDH1A1LMNAHPGDKDM4ESLC9A1 | |
| SCHEMBL1286218 | 0.83 | ALDH1A1 (0.70) | ALDH1A1LMNAHPGDKDM4ESLC9A1 | |
| SCHEMBL2031645 | 0.83 | ALDH1A1 (0.71) | ALDH1A1LMNAHPGDKDM4EPRNP | |
| SCHEMBL3325905 | 0.83 | ALDH1A1 (0.61) | ALDH1A1LMNAHPGDKDM4ESLC9A1 | |
| SCHEMBL9478990 | 0.82 | ERCC5 (0.71) | ALDH1A1LMNAHPGDKDM4ESLC9A1 | |
| SCHEMBL4944134 | 0.82 | SLC9A1 (1.00) | SLC9A1 | |
| SCHEMBL12885825 | 0.81 | ALDH1A1 (0.69) | ALDH1A1LMNAHPGDKDM4EPRNP | |
| SCHEMBL9477782 | 0.81 | ALDH1A1 (0.69) | ALDH1A1LMNAHPGDSLC9A1ERCC5 | |
| SCHEMBL15218337 | 0.81 | ALDH1A1 (0.69) | ALDH1A1LMNAHPGDKDM4EPRNP | |
| SCHEMBL4163540 | 0.81 | ALDH1A1 (0.68) | ALDH1A1LMNAHPGDKDM4EPRNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100345847-C | Novel biarylcarboxamides | ASTRAZENECA AB (SE) | 2007-10-31 | — | — | CN | claimed |
| CN-1400973-A | Novel biarylcarboxamides | ASTRAZENECA AB (SE) | 2003-03-05 | — | — | CN | claimed |
| EP-4596548-A1 | NURR1 MODULATORS | Ludwig-Maximilians-Universität (DE) | 2025-08-06 | — | — | EP | disclosed |
| EP-2512238-B1 | FUSED TRICYCLIC COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | MERCK SHARP & DOHME (US) | 2014-06-25 | — | — | EP | disclosed |
| CN-100345847-C | Novel biarylcarboxamides | ASTRAZENECA AB (SE) | 2007-10-31 | — | — | CN | disclosed |
| CN-1400973-A | Novel biarylcarboxamides | ASTRAZENECA AB (SE) | 2003-03-05 | — | — | CN | disclosed |
| US-20030008867-A1 | Compounds | ASTRAZENECA AB (SE) | 2003-01-09 | — | — | US | disclosed |
| US-5214042-A | Use of 5-phenyl-2-furan esters, amides and ketones as neuroprotective agents | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1993-05-25 | — | — | US | disclosed |
| US-5118708-A | USE OF 5-PHENYL-2-FURAN ESTERS, AMIDES AND KETONES AS NEUROPROTECTIVE AGENTS | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1992-06-02 | — | — | US | disclosed |
| US-5023272-A | Use of 5-phenyl-2-furan esters and amides as antiepileptic agents | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1991-06-11 | — | — | US | disclosed |
| EP-0404231-A1 | The use of 5-phenyl-2 furan esters and amides as antiepileptic agents | Norwich Eaton Pharmaceuticals, Inc. (US) | 1990-12-27 | — | — | EP | disclosed |
| EP-0404233-A2 | Novel use of 5-phenyl-2-furan esters, amides and ketones as neuroprotective agents | Norwich Eaton Pharmaceuticals, Inc. (US) | 1990-12-27 | — | — | EP | disclosed |
| US-4066668-A | 5-(4-CHLOROPHENYL)-2-FURIMIDIC ACID HYDRAZIDES | MORTON-NORWICH PRODUCTS, INC. (US) | 1978-01-03 | — | — | US | disclosed |
| US-4066668-A | 5-(4-CHLOROPHENYL)-2-FURIMIDIC ACID HYDRAZIDES | MORTON-NORWICH PRODUCTS, INC. (US) | 1978-01-03 | — | — | US | disclosed |
| US-4066668-A | 5-(4-CHLOROPHENYL)-2-FURIMIDIC ACID HYDRAZIDES | MORTON-NORWICH PRODUCTS, INC. (US) | 1978-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030008867-A1 | Compounds | DRD2, DRD1, GRIN2A | ALDH1A1 75/4885LMNA 1991/4885HPGD 1662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.