Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | NOS3 | P29474 | 2/20 | 0.50 |
| ▸ | NOS1 | P29475 | 2/20 | 0.50 |
| ▸ | NOS2 | P35228 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2590384 | 0.91 | CA1 (0.58) | MAPTRAB9ANPC1NOS3NOS1 | |
| SCHEMBL3080726 | 0.84 | MAPT (0.75) | MAPTRAB9ANPC1NOS3NOS1 | |
| SCHEMBL3080728 | 0.84 | MAPT (0.75) | MAPTRAB9ANPC1NOS3NOS1 | |
| SCHEMBL12307337 | 0.84 | MAPT (0.61) | MAPTRAB9ANPC1NOS3NOS1 | |
| SCHEMBL15218700 | 0.83 | RAB9A (0.55) | MAPTRAB9ANPC1NOS3NOS1 | |
| SCHEMBL15218703 | 0.80 | MAPT (0.57) | MAPTRAB9ANPC1NOS3NOS1 | |
| SCHEMBL10817298 | 0.80 | RAB9A (0.69) | MAPTRAB9ANPC1NOS3NOS1 | |
| SCHEMBL10025042 | 0.79 | ESR1 (0.79) | MAPTRAB9ANPC1NOS3NOS1 | |
| SCHEMBL15218698 | 0.79 | TRPA1 (0.56) | MAPTRAB9ANPC1NOS1CA12 | |
| SCHEMBL5359003 | 0.79 | MAPT (0.67) | MAPTRAB9ANPC1NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9018362-B2 | Oligonucleotide and use thereof | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2015-04-28 | — | — | US | disclosed |
| US-9018362-B2 | Oligonucleotide and use thereof | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2015-04-28 | — | — | US | disclosed |
| US-20130225797-A1 | OLIGONUCLEOTIDE AND USE THEREOF | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2013-08-29 | — | — | US | disclosed |
| US-20130225797-A1 | OLIGONUCLEOTIDE AND USE THEREOF | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2013-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225797-A1 | OLIGONUCLEOTIDE AND USE THEREOF | NOP2, HNRNPA2B1, NSUN2 | MAPT 4629/4885RAB9A 4515/4885NPC1 3221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.