Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CD69 | Q07108 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1021140 | 0.89 | HTT (0.59) | KMT2AHTTMAPTCA12CA1 | |
| SCHEMBL1548150 | 0.80 | TRPA1 (0.62) | TRPA1NPC1KMT2APOLBMEN1 | |
| SCHEMBL1548149 | 0.80 | TRPA1 (0.62) | TRPA1NPC1KMT2APOLBMEN1 | |
| SCHEMBL15209027 | 0.80 | ALDH1A1 (0.50) | TRPA1NPC1KMT2APOLBMEN1 | |
| SCHEMBL31702246 | 0.79 | TRPA1 (0.86) | TRPA1NPC1KMT2APOLBMEN1 | |
| SCHEMBL70162 | 0.79 | TRPA1 (0.86) | TRPA1NPC1KMT2APOLBMEN1 | |
| SCHEMBL70163 | 0.79 | TRPA1 (0.86) | TRPA1NPC1KMT2APOLBMEN1 | |
| SCHEMBL3364649 | 0.79 | TRPA1 (0.86) | TRPA1NPC1KMT2APOLBMEN1 | |
| SCHEMBL15218699 | 0.79 | TRPA1 (0.51) | TRPA1NPC1KMT2APOLBMEN1 | |
| SCHEMBL15218697 | 0.79 | MAPT (0.57) | NPC1KMT2APOLBMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9018362-B2 | Oligonucleotide and use thereof | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2015-04-28 | — | — | US | disclosed |
| US-9018362-B2 | Oligonucleotide and use thereof | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2015-04-28 | — | — | US | disclosed |
| US-20130225797-A1 | OLIGONUCLEOTIDE AND USE THEREOF | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2013-08-29 | — | — | US | disclosed |
| US-20130225797-A1 | OLIGONUCLEOTIDE AND USE THEREOF | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2013-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225797-A1 | OLIGONUCLEOTIDE AND USE THEREOF | NOP2, HNRNPA2B1, NSUN2 | TRPA1 3471/4885NPC1 3221/4885KMT2A 1585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.