Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PMM2 | O15305 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4464051 | 0.85 | TSHR (0.47) | TSHRCYP3A4GPR35KAT2BVCAM1 | |
| SCHEMBL2107697 | 0.83 | VCAM1 (0.37) | TSHRCYP3A4VCAM1MAPTALDH1A1 | |
| SCHEMBL6380480 | 0.83 | S100A4 (0.40) | GPR35VCAM1SMN1; SMN2KDM4E | |
| SCHEMBL30413307 | 0.83 | ALDH1A1 (0.51) | TSHRCYP3A4VCAM1MEN1MAPT | |
| SCHEMBL17875627 | 0.83 | ALDH1A1 (0.51) | TSHRCYP3A4VCAM1MEN1MAPT | |
| SCHEMBL13931955 | 0.80 | ALDH1A1 (0.47) | SMN1; SMN2MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL1796916 | 0.80 | VCAM1 (0.53) | KAT2BVCAM1MEN1MAPTKMT2A | |
| SCHEMBL709464 | 0.80 | ALDH1A1 (0.42) | GPR35VCAM1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL38666571 | 0.79 | VCAM1 (0.39) | VCAM1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL18825060 | 0.78 | TSHR (0.42) | TSHRCYP3A4GPR35SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946478-B2 | Benzamide derivative with anticancer activity and preparation method and use thereof | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2015-02-03 | — | — | US | disclosed |
| US-20130225810-A1 | BENZAMIDE DERIVATIVE WITH ANTICANCER ACTIVITY AND PREPARATION METHOD AND USE THEREOF | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2013-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225810-A1 | BENZAMIDE DERIVATIVE WITH ANTICANCER ACTIVITY AND PREPARATION METHOD AND USE THEREOF | HDAC5, TMBIM6, HDAC6 | TSHR 4200/4885CYP3A4 350/4885GPR35 3615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.