Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.55 |
| ▸ | PLG | P00747 | 1/20 | 0.54 |
| ▸ | PLAU | P00749 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18792640 | 0.83 | HRH4 (0.51) | HRH4CYP2A6KEAP1KDM4EALDH1A1 | |
| SCHEMBL25139729 | 0.82 | RAB9A (0.68) | HRH4PLGPLAUKDM4EALDH1A1 | |
| SCHEMBL12862877 | 0.81 | HRH4 (0.58) | HRH4CYP2A6KEAP1KDM4EALDH1A1 | |
| SCHEMBL30270477 | 0.81 | KDM4E (0.66) | HRH4PLGPLAUKDM4EALDH1A1 | |
| SCHEMBL2732294 | 0.81 | FLT3 (0.57) | HRH4PLGPLAUKDM4EALDH1A1 | |
| SCHEMBL24196169 | 0.81 | KDM4E (0.66) | HRH4PLGPLAUKDM4EALDH1A1 | |
| SCHEMBL24019647 | 0.81 | F7 (0.66) | HRH4RAB9AFLT3NPC1HRH3 | |
| SCHEMBL12452817 | 0.80 | MAOA (0.51) | PLGPLAUKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL12848263 | 0.80 | ALOX15 (0.58) | HRH4CYP2A6KEAP1KDM4EALDH1A1 | |
| SCHEMBL656018 | 0.80 | KDM4E (0.74) | HRH4CYP2A6KEAP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130224227-A1 | NOVEL CONJUGATES OF CC-1065 ANALOGS AND BIFUNCTIONAL LINKERS | BYONDIS B.V. (NL) | 2013-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130224227-A1 | NOVEL CONJUGATES OF CC-1065 ANALOGS AND BIFUNCTIONAL LINKERS | PCNA, DCLRE1A, CDC5L | HRH4 2715/4885PLG 3678/4885PLAU 4107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.