Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 3/20 | 0.46 |
| ▸ | CD74 | P04233 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11495935 | 0.82 | ADORA1 (0.50) | ADORA1HPGDKDM4ELMNAHTT | |
| SCHEMBL1523079 | 0.80 | TSHR (0.46) | MIFCD74HPGDLMNATSHR | |
| SCHEMBL1522698 | 0.79 | PTGDR2 (0.51) | MIFKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL5871423 | 0.74 | KDM4E (0.58) | ADORA1HPGDKDM4ELMNAHTT | |
| SCHEMBL1523060 | 0.74 | MIF (0.44) | MIFCD74HPGDKDM4ELMNA | |
| SCHEMBL1523149 | 0.73 | MIF (0.53) | MIFCD74KDM4ELMNATSHR | |
| SCHEMBL1522607 | 0.73 | MIF (0.66) | MIFCD74KDM4EMEN1KMT2A | |
| SCHEMBL1522225 | 0.73 | PTGDR2 (0.55) | HPGDKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1522725 | 0.73 | MIF (0.41) | MIFCD74HPGDKDM4ELMNA | |
| SCHEMBL1522614 | 0.72 | ALDH1A1 (0.57) | MIFCD74HPGDLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361913-A1 | Anti-infective agents | Abbott Laboratories (US) | 2011-08-31 | — | — | EP | disclosed |
| US-7902203-B2 | Anti-infective agents | ABBOTT LABORATORIES, INC. (US) | 2011-03-08 | — | — | US | disclosed |
| EP-1560827-B1 | ANTI-INFECTIVE AGENTS | ABBOTT LAB (US) | 2010-12-29 | — | — | EP | disclosed |
| US-20050075331-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2005-04-07 | — | — | US | disclosed |
| US-20040167123-A1 | Anti-infective agents | ABBVIE INC. | 2004-08-26 | — | — | US | disclosed |
| US-20040162285-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-08-19 | — | — | US | disclosed |
| US-20040097492-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-20 | — | — | US | disclosed |
| US-20040087577-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097492-A1 | Anti-infective agents | POLR1C, RPL5, POLB | ADORA1 4282/4885MIF 1032/4885CD74 399/4885 |
| US-20040162285-A1 | Anti-infective agents | POLR1C, RPL5, POLB | ADORA1 4282/4885MIF 1032/4885CD74 399/4885 |
| US-20040167123-A1 | Anti-infective agents | SERPINB1, CYP51A1, ZC3HAV1 | ADORA1 3326/4885MIF 188/4885CD74 384/4885 |
| US-20050075331-A1 | Anti-infective agents | RPL35, POLI, POLRMT | ADORA1 4172/4885MIF 243/4885CD74 236/4885 |
| US-20040087577-A1 | Anti-infective agents | POLR1C, RPL5, POLB | ADORA1 4282/4885MIF 1032/4885CD74 399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.