Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 3/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | CD74 | P04233 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11156065 | 0.81 | PDE5A (0.47) | TSHRALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL1522428 | 0.80 | ADORA1 (0.46) | TSHRALDH1A1HPGDHSD17B10MIF | |
| SCHEMBL1227299 | 0.78 | MAP4K1 (0.48) | TSHRNPSR1ALDH1A1MAPTPOLB | |
| SCHEMBL2354496 | 0.77 | F7 (0.33) | ELANEMEN1KMT2A | |
| SCHEMBL11165276 | 0.77 | ALDH1A1 (0.39) | TSHRALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL23141918 | 0.75 | CDK4 (0.60) | TSHRNPSR1ALDH1A1MAPTPOLB | |
| SCHEMBL30718958 | 0.75 | CDK4 (0.60) | TSHRNPSR1ALDH1A1MAPTPOLB | |
| SCHEMBL26125659 | 0.73 | PDE4A (0.42) | TSHRNPSR1ALDH1A1MAPTPOLB | |
| SCHEMBL11168022 | 0.73 | SMN1; SMN2 (0.46) | TSHRNPSR1ALDH1A1MAPTPOLB | |
| SCHEMBL4261897 | 0.73 | MEN1 (0.45) | TSHRNPSR1ALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361913-A1 | Anti-infective agents | Abbott Laboratories (US) | 2011-08-31 | — | — | EP | disclosed |
| US-7902203-B2 | Anti-infective agents | ABBOTT LABORATORIES, INC. (US) | 2011-03-08 | — | — | US | disclosed |
| EP-1560827-B1 | ANTI-INFECTIVE AGENTS | ABBOTT LAB (US) | 2010-12-29 | — | — | EP | disclosed |
| US-20050075331-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2005-04-07 | — | — | US | disclosed |
| US-20040167123-A1 | Anti-infective agents | ABBVIE INC. | 2004-08-26 | — | — | US | disclosed |
| US-20040162285-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-08-19 | — | — | US | disclosed |
| US-20040097492-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-20 | — | — | US | disclosed |
| US-20040087577-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097492-A1 | Anti-infective agents | POLR1C, RPL5, POLB | TSHR 4415/4885NPSR1 4323/4885ALDH1A1 1434/4885 |
| US-20040162285-A1 | Anti-infective agents | POLR1C, RPL5, POLB | TSHR 4415/4885NPSR1 4323/4885ALDH1A1 1434/4885 |
| US-20040167123-A1 | Anti-infective agents | SERPINB1, CYP51A1, ZC3HAV1 | TSHR 4722/4885NPSR1 4037/4885ALDH1A1 891/4885 |
| US-20050075331-A1 | Anti-infective agents | RPL35, POLI, POLRMT | TSHR 4644/4885NPSR1 4146/4885ALDH1A1 1592/4885 |
| US-20040087577-A1 | Anti-infective agents | POLR1C, RPL5, POLB | TSHR 4415/4885NPSR1 4323/4885ALDH1A1 1434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.