Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15224344 | 1.00 | PTPN1 (0.34) | PTPN1RXRAHIF1AALDH1A1CYP3A4 | |
| SCHEMBL15224302 | 0.88 | PTPN1 (0.33) | PTPN1RXRAHIF1A | |
| SCHEMBL15224348 | 0.88 | PTPN1 (0.33) | PTPN1RXRAHIF1A | |
| SCHEMBL15224833 | 0.86 | HIF1A (0.33) | PTPN1RXRAHIF1AALDH1A1CYP3A4 | |
| SCHEMBL15249294 | 0.82 | PTPN1 (0.39) | PTPN1RXRAHIF1A | |
| SCHEMBL31058467 | 0.82 | PTPN1 (0.39) | PTPN1RXRAHIF1A | |
| SCHEMBL15224303 | 0.74 | HIF1A (0.32) | PTPN1RXRAHIF1A | |
| SCHEMBL15281214 | 0.65 | AKR1B10 (0.34) | ALDH1A1 | |
| SCHEMBL13425366 | 0.64 | PTPN1 (0.42) | PTPN1RXRAALDH1A1 | |
| SCHEMBL15397968 | 0.62 | AKR1C3 (0.54) | PTPN1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2633886-B1 | COMPOUNDS AND MIXTURES INFLUENCING INFLAMMATORY STATES | SYMRISE AG (DE) | 2018-01-31 | — | — | EP | disclosed |
| US-8906958-B2 | Compounds and mixtures for influencing inflammatory states | SYMRISE AG (DE) | 2014-12-09 | — | — | US | disclosed |
| US-20130251730-A1 | Compounds and Mixtures Influencing Inflammatory States | SYMRISE AG (DE) | 2013-09-26 | — | — | US | disclosed |
| US-20130236472-A1 | COMPOUNDS AND MIXTURES FOR INFLUENCING INFLAMMATORY STATES | SYMRISE AG (DE) | 2013-09-12 | — | — | US | disclosed |
| EP-2633885-A1 | Compounds and mixtures for affecting inflammatory conditions | Symrise AG (DE) | 2013-09-04 | — | — | EP | disclosed |
| EP-2633886-A1 | Compounds and mixtures influencing inflammatory states | Symrise AG (DE) | 2013-09-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130251730-A1 | Compounds and Mixtures Influencing Inflammatory States | MSR1, MPO, IL1B | PTPN1 1659/4885RXRA 389/4885HIF1A 240/4885 |
| US-20130236472-A1 | COMPOUNDS AND MIXTURES FOR INFLUENCING INFLAMMATORY STATES | TNF, CXCL8, IL1B | PTPN1 1460/4885RXRA 333/4885HIF1A 632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.