Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 3/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 3/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1522680 | 0.99 | DDB1 (0.42) | DDB1CRBNPDE4BPDE4DALDH1A1 | |
| SCHEMBL1522771 | 0.99 | DDB1 (0.42) | DDB1CRBNPDE4BPDE4DALDH1A1 | |
| SCHEMBL1522242 | 0.76 | OPRL1 (0.43) | ALDH1A1KDM4EOPRM1OPRK1OPRL1 | |
| SCHEMBL10846917 | 0.75 | NPSR1 (0.51) | ALDH1A1KMT2AKDM4EGAAALOX15 | |
| SCHEMBL1523280 | 0.74 | ALDH1A1 (0.40) | ALDH1A1KDM4EOPRM1OPRK1OPRL1 | |
| SCHEMBL1522720 | 0.74 | ENPP2 (0.46) | KDM4EOPRM1OPRK1OPRL1TSHR | |
| SCHEMBL1522318 | 0.73 | KDM4E (0.39) | DDB1CRBNALDH1A1KDM4EOPRM1 | |
| SCHEMBL5871425 | 0.72 | PDE4B (0.42) | DDB1CRBNPDE4BPDE4DALDH1A1 | |
| SCHEMBL11240235 | 0.72 | FEN1 (0.51) | PDE4BPDE4DALDH1A1KMT2AKDM4E | |
| SCHEMBL1522773 | 0.72 | FEN1 (0.55) | PDE4BPDE4DALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361913-A1 | Anti-infective agents | Abbott Laboratories (US) | 2011-08-31 | — | — | EP | disclosed |
| US-7902203-B2 | Anti-infective agents | ABBOTT LABORATORIES, INC. (US) | 2011-03-08 | — | — | US | disclosed |
| EP-1560827-B1 | ANTI-INFECTIVE AGENTS | ABBOTT LAB (US) | 2010-12-29 | — | — | EP | disclosed |
| US-20050075331-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2005-04-07 | — | — | US | disclosed |
| US-20040167123-A1 | Anti-infective agents | ABBVIE INC. | 2004-08-26 | — | — | US | disclosed |
| US-20040162285-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-08-19 | — | — | US | disclosed |
| US-20040097492-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-20 | — | — | US | disclosed |
| US-20040087577-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097492-A1 | Anti-infective agents | POLR1C, RPL5, POLB | DDB1 1079/4885CRBN 4386/4885PDE4B 3768/4885 |
| US-20040162285-A1 | Anti-infective agents | POLR1C, RPL5, POLB | DDB1 1079/4885CRBN 4386/4885PDE4B 3768/4885 |
| US-20040167123-A1 | Anti-infective agents | SERPINB1, CYP51A1, ZC3HAV1 | DDB1 908/4885CRBN 4629/4885PDE4B 3431/4885 |
| US-20050075331-A1 | Anti-infective agents | RPL35, POLI, POLRMT | DDB1 1722/4885CRBN 4518/4885PDE4B 3133/4885 |
| US-20040087577-A1 | Anti-infective agents | POLR1C, RPL5, POLB | DDB1 1079/4885CRBN 4386/4885PDE4B 3768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.