Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MET | P08581 | 14/20 | 0.38 |
| ▸ | KDR | P35968 | 12/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | FPR3 | P25089 | 1/20 | 0.35 |
| ▸ | GPR183 | P32249 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3564192 | 0.73 | MET (0.64) | METKDRFLT1FLT4AURKA | |
| SCHEMBL15225920 | 0.73 | MET (0.46) | ALDH1A1METKDRFLT1FLT4 | |
| SCHEMBL3577378 | 0.65 | MET (0.59) | METKDRFLT1FLT4AURKA | |
| SCHEMBL6208938 | 0.63 | CNR2 (0.41) | CNR2 | |
| SCHEMBL3561466 | 0.59 | MET (0.69) | ALDH1A1LMNAMETKDR | |
| SCHEMBL25130188 | 0.59 | MEN1 (0.71) | ALDH1A1LMNAGAAMAPT | |
| SCHEMBL14045085 | 0.59 | ALDH1A1 (0.68) | ALDH1A1LMNAGAAMAPT | |
| SCHEMBL10866850 | 0.57 | ALDH1A1 (0.66) | ALDH1A1LMNAGAAMAPT | |
| SCHEMBL14817526 | 0.57 | SIGMAR1 (0.47) | ALDH1A1LMNACNR2GAAMAPT | |
| SCHEMBL6827496 | 0.56 | RAB9A (0.53) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781664-B1 | INHIBITORS OF VEGF RECEPTOR AND HGF RECEPTOR SIGNALING | METHYLGENE INC (CA) | 2013-09-04 | — | — | EP | disclosed |