SCHEMBL15230356

SCHEMBL15230356

CC(C)(C)OC(=O)N1CC2(C1)CN(c1nc(C3=NOC(c4c(F)cccc4F)C3)cs1)C2

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FAAH O00519 19/20 0.47
USP30 Q70CQ3 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2268188 0.87 FAAH (0.48) FAAHUSP30
SCHEMBL21733016 0.80 FAAH (0.60) FAAH
SCHEMBL20542436 0.80 FAAH (0.60) FAAH
Hydrochloric Acid SCHEMBL15231133 0.80 FAAH (0.43) FAAH
SCHEMBL15230625 0.80 FAAH (0.46) FAAHUSP30
SCHEMBL15230566 0.79 FAAH (0.40) FAAH
SCHEMBL15230699 0.79 FAAH (0.40) FAAH
SCHEMBL15230099 0.77 FAAH (0.40) FAAH
SCHEMBL28860653 0.75 FAAH (0.56) FAAH
SCHEMBL2000000 0.74 FAAH (0.54) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150065481-A1 MICROBIOCIDAL PYRAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2015-03-05 US disclosed
EP-2820011-A1 MICROBIOCIDAL PYRAZOLE DERIVATIVES Syngenta Participations AG (CH) 2015-01-07 EP disclosed
WO-2013127789-A1 MICROBIOCIDAL PYRAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2013-09-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150065481-A1 MICROBIOCIDAL PYRAZOLE DERIVATIVES PRF1, CASP1, MPO FAAH 1071/4885USP30 3648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.