SCHEMBL15313278

SCHEMBL15313278

CC(C)CC(C)(C(N)=O)c1cc(O)no1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RET P07949 1/20 0.33
EGFR P00533 1/20 0.33
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10258408 0.69 EGFR (0.31) EGFR
SCHEMBL23309165 0.68 MEN1 (0.32) EGFR
SCHEMBL4752915 0.67 MEN1 (0.47) EGFR
SCHEMBL2338585 0.65 MAPT (0.53)
SCHEMBL19152162 0.65 EGFR (0.35) EGFR
SCHEMBL23309191 0.64 MEN1 (0.32) EGFR
SCHEMBL2402694 0.64 EPHX1 (0.33) RET
SCHEMBL24743767 0.63
SCHEMBL3279399 0.63 EGFR (0.33) EGFR
SCHEMBL3286005 0.63 EGFR (0.33) EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9670150-B2 (2-ureidoacetamido)alkyl derivatives as formyl peptide receptor 2 modulators ALLERGAN, INC. (US) 2017-06-06 US disclosed
US-20130274230-A1 (2-UREIDOACETAMIDO)ALKYL DERIVATIVES AS FORMYL PEPTIDE RECEPTOR 2 MODULATORS ALLERGAN, INC. (US) 2013-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130274230-A1 (2-UREIDOACETAMIDO)ALKYL DERIVATIVES AS FORMYL PEPTIDE RECEPTOR 2 MODULATORS FPR2, FPR3, FPR1 RET 614/4885EGFR 525/4885CNR1 261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.