⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidine SCHEMBL5102 | 0.78 | — | — | |
| Guanidine SCHEMBL9661571 | 0.78 | ACHE (0.55) | — | |
| Guanidine SCHEMBL1319550 | 0.78 | ACHE (0.55) | — | |
| Guanidine SCHEMBL14677179 | 0.78 | ACHE (0.55) | — | |
| Guanidine SCHEMBL27640020 | 0.75 | — | — | |
| Guanidine SCHEMBL28378215 | 0.75 | ACHE (0.50) | — | |
| Guanidine SCHEMBL5696251 | 0.75 | — | — | |
| Guanidine SCHEMBL8573951 | 0.75 | LMNA (0.55) | — | |
| Guanidine SCHEMBL7757618 | 0.75 | — | — | |
| Guanidine SCHEMBL165720 | 0.72 | NOS2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2480526-A1 | CRYSTALLINE FORMS AND PROCESSES FOR THE PREPARATION OF PGI2 RECEPTOR AGONISTS | Arena Pharmaceuticals, Inc. (US) | 2012-08-01 | — | — | EP | claimed |
| WO-2011037613-A1 | CRYSTALLINE FORMS AND PROCESSES FOR THE PREPARATION OF PGI2 RECEPTOR AGONISTS | ARENA PHARMACEUTICALS, INC. (US) | 2011-03-31 | — | — | WO | claimed |
| CN-219630243-U | Drinking water deodorization and deodorization reaction tank | 四川省国乐食品有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-115894472-A | Preparation method of high-purity azilsartan medoxomil potassium salt | 仁合益康集团有限公司 | 2023-04-04 | — | — | CN | disclosed |
| US-20120225937-A1 | CRYSTALLINE FORMS AND PROCESSES FOR THE PREPARATION OF PG12 RECEPTOR AGONISTS | ARENA PHARMACEUTICALS, INC. (US) | 2012-09-06 | — | — | US | disclosed |
| EP-2480526-A1 | CRYSTALLINE FORMS AND PROCESSES FOR THE PREPARATION OF PGI2 RECEPTOR AGONISTS | Arena Pharmaceuticals, Inc. (US) | 2012-08-01 | — | — | EP | disclosed |
| CN-102015647-A | Process for production of compound having antagonistic activity on NPYY5 receptor, and useful crystal | SHIONOGI & CO | 2011-04-13 | — | — | CN | disclosed |
| WO-2011037613-A1 | CRYSTALLINE FORMS AND PROCESSES FOR THE PREPARATION OF PGI2 RECEPTOR AGONISTS | ARENA PHARMACEUTICALS, INC. (US) | 2011-03-31 | — | — | WO | disclosed |