Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | DDX3X | O00571 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | CD74 | P04233 | 1/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17978485 | 0.84 | P2RX7 (0.74) | P2RX7L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21974270 | 0.84 | RXRA (0.68) | P2RX7NOTUMDDX3XRXRAGRIN1 | |
| SCHEMBL20445076 | 0.83 | NOTUM (0.62) | P2RX7L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29828653 | 0.83 | P2RX7 (0.67) | P2RX7L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3777938 | 0.81 | NOTUM (0.68) | P2RX7L3MBTL1NPC1NOTUMMAOA | |
| Bromide SCHEMBL1882333 | 0.80 | NOTUM (0.66) | P2RX7L3MBTL1NPC1NOTUMMAOA | |
| SCHEMBL15316362 | 0.79 | GLA (0.61) | P2RX7L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28309771 | 0.79 | CA9 (0.71) | L3MBTL1NPC1RAB9ASMN1; SMN2NOTUM | |
| SCHEMBL17978607 | 0.79 | P2RX7 (0.65) | P2RX7L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12601113 | 0.78 | NOTUM (0.64) | P2RX7L3MBTL1NPC1NOTUMMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110563659-B | Method for preparing 1,2, 3-triazole compound by heterogeneous copper catalysis in one pot | 浙江工业大学 | 2020-08-21 | — | — | CN | disclosed |
| CN-110563659-A | Method for preparing 1,2, 3-triazole compound by heterogeneous copper catalysis in one pot | 浙江工业大学 | 2019-12-13 | — | — | CN | disclosed |
| US-20130274212-A1 | Sesterterpene Compounds and Use Thereof | SNU R&DB FOUNDATION (KR) | 2013-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274212-A1 | Sesterterpene Compounds and Use Thereof | LIPC, LIPE, FABP4 | P2RX7 4764/4885L3MBTL1 2672/4885NPC1 458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.