SCHEMBL153176

SCHEMBL153176

N#CC1CCC(N(Cc2ccccc2)Cc2ccccc2)C1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
YTHDC1 Q96MU7 1/20 0.43
ALDH1A1 P00352 1/20 0.42
SLC6A4 P31645 3/20 0.39
SLC6A2 P23975 2/20 0.39
SLC6A3 Q01959 1/20 0.39
RORC P51449 2/20 0.37
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.36
GRIN2B Q13224 1/20 0.36
RAB9A P51151 1/20 0.36
DPP8 Q6V1X1 1/20 0.36
DPP7 Q9UHL4 1/20 0.36
G6PC1 P35575 1/20 0.36
DRD2 P14416 1/20 0.35
DRD3 P35462 1/20 0.35
NAAA Q02083 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ATM Q13315 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL154511 0.91 GRIN2B (0.47) YTHDC1ALDH1A1SLC6A4SLC6A2RORC
SCHEMBL1543051 0.90 YTHDC1 (0.48) YTHDC1ALDH1A1SLC6A4SLC6A2SLC6A3
SCHEMBL150705 0.90 YTHDC1 (0.48) YTHDC1ALDH1A1SLC6A4SLC6A2SLC6A3
SCHEMBL149289 0.84 SLC6A4 (0.48) ALDH1A1SLC6A4SLC6A2SLC6A3GRIN2B
SCHEMBL150922 0.81 GRIN2B (0.52) YTHDC1ALDH1A1SLC6A4SLC6A2RORC
SCHEMBL3376962 0.78 YTHDC1 (0.58) YTHDC1ALDH1A1SLC6A4SLC6A2SLC6A3
SCHEMBL150082 0.77 NAAA (0.50) ALDH1A1SLC6A4RORCGRIN2BNAAA
SCHEMBL21733441 0.77 YTHDC1 (0.48) YTHDC1ALDH1A1SLC6A4SLC6A2SLC6A3
SCHEMBL21774844 0.77 YTHDC1 (0.48) YTHDC1ALDH1A1SLC6A4SLC6A2SLC6A3
SCHEMBL16751796 0.75 AGER (0.46) RORCKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2526149-B1 POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP BRIDGESTONE CORP (JP) 2017-03-01 EP disclosed
US-9469710-B2 Polymers functionalized with nitrile compounds containing a protected amino group BRIDGESTONE CORPORATION (JP) 2016-10-18 US disclosed
US-20150148489-A1 POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2015-05-28 US disclosed
US-8735494-B2 Polymers functionalized with nitrile compounds containing a protected amino group BRIDGESTONE CORPORATION (JP) 2014-05-27 US disclosed
US-20130085227-A1 POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2013-04-04 US disclosed
US-8344066-B2 Polymers functionalized with nitrile compounds containing a protected amino group BRIDGESTONE CORPORATION (JP) 2013-01-01 US disclosed
US-20120296041-A1 POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2012-11-22 US disclosed
US-20120059112-A1 POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS COMTAINING A PROTECTED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2012-03-08 US disclosed
EP-2382240-A2 POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP Bridgestone Corporation (JP) 2011-11-02 EP disclosed
WO-2011091346-A2 POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2011-07-28 WO disclosed
WO-2010085622-A9 POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2010-12-23 WO disclosed
WO-2010085622-A2 POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2010-07-29 WO disclosed