Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15318100 | 0.75 | MEN1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL30887172 | 0.73 | CA12 (0.41) | TLR7CA12CA1CA2CA9 | |
| SCHEMBL15672423 | 0.70 | TDP1 (0.36) | — | |
| SCHEMBL16674126 | 0.66 | HSP90AA1 (0.38) | — | |
| SCHEMBL14268588 | 0.64 | TDP1 (0.38) | — | |
| SCHEMBL15985647 | 0.62 | ALDH1A1 (0.30) | — | |
| SCHEMBL15177503 | 0.60 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL19822481 | 0.58 | ALDH1A1 (0.59) | — | |
| SCHEMBL11519365 | 0.58 | KDM4C (0.56) | KDM4C | |
| SCHEMBL19822472 | 0.57 | NPC1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9028880-B2 | Silica nanoparticle agent conjugates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2015-05-12 | — | — | US | disclosed |
| US-20130274226-A1 | SILICA NANOPARTICLE AGENT CONJUGATES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2013-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274226-A1 | SILICA NANOPARTICLE AGENT CONJUGATES | TST, NCL, MSN | TLR7 3725/4885CA12 278/4885CA1 427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.