Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15320015 | 0.80 | ACHE (0.40) | ALDH1A1PARP10PARP11 | |
| SCHEMBL15319396 | 0.75 | GID4 (0.41) | GID4KDM4EALDH1A1PARP10PARP11 | |
| SCHEMBL16534360 | 0.75 | PDE5A (0.39) | GID4KDM4EALDH1A1 | |
| SCHEMBL15321555 | 0.72 | ADRA2A (0.40) | ALDH1A1 | |
| SCHEMBL20153040 | 0.69 | OPRM1 (0.41) | KDM1A | |
| SCHEMBL2968862 | 0.69 | ALDH1A1 (0.38) | GID4KDM4EALDH1A1BRD4KDM1A | |
| SCHEMBL17969853 | 0.68 | GID4 (0.45) | GID4KDM4EALDH1A1PARP10PARP11 | |
| SCHEMBL15319240 | 0.68 | KDM4E (0.37) | GID4KDM4EALDH1A1BRD4KDM1A | |
| SCHEMBL16349504 | 0.67 | ALDH1A1 (0.36) | GID4KDM4EALDH1A1BRD4KDM1A | |
| SCHEMBL1321294 | 0.67 | ALDH1A1 (0.36) | GID4KDM4EALDH1A1BRD4PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2834233-A1 | NEW ALPHA2 ADRENOCEPTOR AGONISTS | Orion Corporation (FI) | 2015-02-11 | — | — | EP | disclosed |
| WO-2013150173-A1 | NEW ALPHA2 ADRENOCEPTOR AGONISTS | ORION CORPORATION (FI) | 2013-10-10 | — | — | WO | disclosed |