Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL1532267 | 0.89 | LMNA (0.61) | LMNATAAR1KDM4EL3MBTL1HTR3A | |
| SCHEMBL175554 | 0.81 | TAAR1 (0.62) | LMNATAAR1KDM4EL3MBTL1HTR3A | |
| SCHEMBL147501 | 0.81 | TAAR1 (0.62) | LMNATAAR1KDM4EL3MBTL1HTR3A | |
| SCHEMBL2021 | 0.81 | TAAR1 (0.62) | LMNATAAR1KDM4EL3MBTL1HTR3A | |
| Ammonia Solution, Strong SCHEMBL27544022 | 0.79 | TAAR1 (0.60) | LMNATAAR1KDM4EL3MBTL1HTR3A | |
| Hydrochloric Acid SCHEMBL7153880 | 0.79 | KDM4E (0.64) | LMNATAAR1KDM4EL3MBTL1HTR3A | |
| Hydrochloric Acid SCHEMBL8178381 | 0.79 | KDM4E (0.64) | LMNATAAR1KDM4EL3MBTL1HTR3A | |
| Hydrochloric Acid SCHEMBL29175850 | 0.79 | KDM4E (0.64) | LMNATAAR1KDM4EL3MBTL1HTR3A | |
| Bromide SCHEMBL29131747 | 0.79 | TAAR1 (0.60) | LMNATAAR1KDM4EL3MBTL1HTR3A | |
| Monoethanolamine SCHEMBL9507297 | 0.77 | TAAR1 (0.54) | LMNATAAR1KDM4EL3MBTL1HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101513402-A | Antiviral agent | SHIONOGI & CO (JP) | 2009-08-26 | — | — | CN | disclosed |
| CN-100491349-C | Antiviral agent | SHIONOGI & CO (JP) | 2009-05-27 | — | — | CN | disclosed |
| CN-1558898-A | Antiviral agent | ��Ұ����ҩ��ʽ���� | 2004-12-29 | — | — | CN | disclosed |
| CN-1461187-A | Method for reducing pollen fertility by using pollen-specific zinc finger transcription factor gene | INST OF AGROBIOLOGICAL RESOURC (JP) | 2003-12-10 | — | — | CN | disclosed |