Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15322852 | 1.00 | NOS1 (0.54) | NOS1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL15323282 | 0.84 | NOS3 (0.62) | NOS1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL15323278 | 0.84 | NOS3 (0.62) | NOS1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL15323697 | 0.84 | MAPT (0.57) | RAB9AMEN1KMT2ANPC1MAPT | |
| SCHEMBL15323693 | 0.84 | MAPT (0.57) | RAB9AMEN1KMT2ANPC1MAPT | |
| SCHEMBL15322435 | 0.84 | KMT2A (0.61) | NOS1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL15322433 | 0.84 | KMT2A (0.61) | NOS1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL9423004 | 0.83 | RAB9A (0.52) | NOS1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL9423002 | 0.83 | RAB9A (0.52) | NOS1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL24105687 | 0.83 | NOS3 (0.64) | NOS1RAB9AMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150073165-A1 | CATALYST COMPOUNDS | THE UNIVIERSITY OF LIVERPOOL (GB) | 2015-03-12 | — | — | US | disclosed |
| EP-2836496-A1 | CATALYST COMPOUNDS | The University of Liverpool (GB) | 2015-02-18 | — | — | EP | disclosed |
| WO-2013153408-A1 | CATALYST COMPOUNDS | THE UNIVERSITY OF LIVERPOOL (GB) | 2013-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150073165-A1 | CATALYST COMPOUNDS | NQO1, IDH2, IDH3B | NOS1 602/4885RAB9A 1020/4885MEN1 262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.