Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15322929 | 1.00 | HPGDS (0.56) | HPGDSMAPTTP53CASP3SENP8 | |
| SCHEMBL20645901 | 0.84 | HPGDS (0.53) | HPGDSMAPTTP53CASP3SENP8 | |
| SCHEMBL28418174 | 0.84 | HPGDS (0.53) | HPGDSMAPTTP53CASP3SENP8 | |
| SCHEMBL9553319 | 0.80 | MMP9 (0.65) | MAPTTP53KDM4EHPGDALDH1A1 | |
| SCHEMBL14097075 | 0.79 | ALPL (0.52) | HPGDSMAPTTP53CASP3SENP8 | |
| SCHEMBL595997 | 0.75 | ALPL (0.75) | HPGDSMAPTTP53CASP3SENP8 | |
| SCHEMBL13039697 | 0.74 | ADORA3 (0.49) | MAPTKDM4EHPGDALDH1A1KMT2A | |
| SCHEMBL1456726 | 0.74 | HPGDS (0.58) | HPGDSMAPTTP53CASP3SENP8 | |
| SCHEMBL16112173 | 0.73 | HPGDS (0.59) | HPGDSMAPTTP53CASP3SENP8 | |
| SCHEMBL7421798 | 0.73 | ALDH1A1 (0.52) | MAPTKDM4EHPGDALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013149997-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS WITH ACTIVITY TOWARDS EP1 RECEPTORS | ALMIRALL, S.A. (ES) | 2013-10-10 | — | — | WO | disclosed |