Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.30 |
| ▸ | FAP | Q12884 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25397085 | 0.79 | ADRB2 (0.36) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL6894684 | 0.74 | DPP4 (0.38) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL137918 | 0.69 | DPP4 (0.34) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL8941804 | 0.69 | DPP4 (0.40) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL139232 | 0.68 | DPP4 (0.35) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL138094 | 0.67 | DPP4 (0.38) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL15322537 | 0.66 | ADRB2 (0.30) | — | |
| SCHEMBL28288006 | 0.66 | NOS2 (0.42) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL28992550 | 0.65 | NOS2 (0.38) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL25415498 | 0.65 | CYP3A4 (0.41) | DPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836833-A1 | PRENATAL SCREENING FOR DOWN SYNDROME AND TRISOMY 18 | Wayne State University (US) | 2015-02-18 | — | — | EP | disclosed |
| WO-2013155456-A1 | PRENATAL SCREENING FOR DOWN SYNDROME AND TRISOMY 18 | WAYNE STATE UNIVERSITY (US) | 2013-10-17 | — | — | WO | disclosed |