Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15003946 | 1.00 | ALDH1A1 (0.60) | ALDH1A1KMT2AMEN1LMNANPC1 | |
| SCHEMBL15003942 | 0.84 | ALDH1A1 (0.82) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL6687727 | 0.84 | ALDH1A1 (0.82) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL15325817 | 0.83 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1LMNANPC1 | |
| SCHEMBL5030292 | 0.81 | CRHBP (0.62) | ALDH1A1KMT2AMEN1LMNANPC1 | |
| SCHEMBL8364606 | 0.81 | CRHBP (0.62) | ALDH1A1KMT2AMEN1LMNANPC1 | |
| SCHEMBL7860138 | 0.81 | CRHBP (0.58) | ALDH1A1KMT2AMEN1LMNARAB9A | |
| Hydrochloric Acid SCHEMBL28749182 | 0.81 | KCNH3 (0.50) | ALDH1A1KMT2AMEN1LMNANPC1 | |
| SCHEMBL1195949 | 0.79 | MAPT (0.68) | ALDH1A1KMT2AMEN1LMNANPC1 | |
| SCHEMBL25185020 | 0.79 | CNR1 (0.57) | ALDH1A1KMT2AMEN1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9212199-B2 | Catalyst compounds | THE UNIVERSITY OF LIVERPOOL (GB) | 2015-12-15 | — | — | US | disclosed |
| US-9212199-B2 | Catalyst compounds | THE UNIVERSITY OF LIVERPOOL (GB) | 2015-12-15 | — | — | US | disclosed |
| US-20150080592-A1 | CATALYST COMPOUNDS | THE UNIVERSITY OF LIVERPOOL (GB) | 2015-03-19 | — | — | US | disclosed |
| US-20150080592-A1 | CATALYST COMPOUNDS | THE UNIVERSITY OF LIVERPOOL (GB) | 2015-03-19 | — | — | US | disclosed |
| US-20150073165-A1 | CATALYST COMPOUNDS | THE UNIVIERSITY OF LIVERPOOL (GB) | 2015-03-12 | — | — | US | disclosed |
| US-20150073165-A1 | CATALYST COMPOUNDS | THE UNIVIERSITY OF LIVERPOOL (GB) | 2015-03-12 | — | — | US | disclosed |
| WO-2013153407-A1 | CATALYST COMPOUNDS | THE UNIVERSITY OF LIVERPOOL (GB) | 2013-10-17 | — | — | WO | disclosed |
| WO-2013153408-A1 | CATALYST COMPOUNDS | THE UNIVERSITY OF LIVERPOOL (GB) | 2013-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150073165-A1 | CATALYST COMPOUNDS | NQO1, IDH2, IDH3B | ALDH1A1 115/4885KMT2A 1536/4885MEN1 262/4885 |
| US-20150080592-A1 | CATALYST COMPOUNDS | IDH3B, IDH2, NQO1 | ALDH1A1 261/4885KMT2A 1132/4885MEN1 294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.