Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15325818 | 0.83 | ALDH1A1 (0.60) | ALDH1A1MAPK1NPSR1MAPTNPC1 | |
| SCHEMBL15003946 | 0.83 | ALDH1A1 (0.60) | ALDH1A1MAPK1NPSR1MAPTNPC1 | |
| SCHEMBL7788967 | 0.80 | MAPK1 (0.51) | ALDH1A1MAPK1NPSR1MAPTNPC1 | |
| SCHEMBL7785304 | 0.79 | MAPK1 (0.48) | ALDH1A1MAPK1NPSR1MAPTNPC1 | |
| SCHEMBL27556854 | 0.79 | MAPK1 (0.48) | ALDH1A1MAPK1NPSR1MAPTNPC1 | |
| SCHEMBL27540196 | 0.78 | ACP3 (0.50) | ALDH1A1MAPK1NPSR1MAPTNPC1 | |
| SCHEMBL7785642 | 0.78 | ACP3 (0.50) | ALDH1A1MAPK1NPSR1MAPTNPC1 | |
| SCHEMBL6885401 | 0.77 | ALDH1A1 (0.69) | ALDH1A1NPSR1MAPTNPC1RAB9A | |
| SCHEMBL7789425 | 0.77 | NFE2L2 (0.55) | ALDH1A1MAPK1NPSR1MAPTNPC1 | |
| SCHEMBL7801278 | 0.77 | NFE2L2 (0.55) | ALDH1A1MAPK1NPSR1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836497-B1 | CATALYST COMPOUNDS | UNIV LIVERPOOL (GB) | 2016-03-23 | — | — | EP | disclosed |
| US-9212199-B2 | Catalyst compounds | THE UNIVERSITY OF LIVERPOOL (GB) | 2015-12-15 | — | — | US | disclosed |
| US-9212199-B2 | Catalyst compounds | THE UNIVERSITY OF LIVERPOOL (GB) | 2015-12-15 | — | — | US | disclosed |
| US-20150080592-A1 | CATALYST COMPOUNDS | THE UNIVERSITY OF LIVERPOOL (GB) | 2015-03-19 | — | — | US | disclosed |
| US-20150080592-A1 | CATALYST COMPOUNDS | THE UNIVERSITY OF LIVERPOOL (GB) | 2015-03-19 | — | — | US | disclosed |
| US-20150073165-A1 | CATALYST COMPOUNDS | THE UNIVIERSITY OF LIVERPOOL (GB) | 2015-03-12 | — | — | US | disclosed |
| US-20150073165-A1 | CATALYST COMPOUNDS | THE UNIVIERSITY OF LIVERPOOL (GB) | 2015-03-12 | — | — | US | disclosed |
| WO-2013153407-A1 | CATALYST COMPOUNDS | THE UNIVERSITY OF LIVERPOOL (GB) | 2013-10-17 | — | — | WO | disclosed |
| WO-2013153408-A1 | CATALYST COMPOUNDS | THE UNIVERSITY OF LIVERPOOL (GB) | 2013-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150073165-A1 | CATALYST COMPOUNDS | NQO1, IDH2, IDH3B | ALDH1A1 115/4885MAPK1 2307/4885NPSR1 2974/4885 |
| US-20150080592-A1 | CATALYST COMPOUNDS | IDH3B, IDH2, NQO1 | ALDH1A1 261/4885MAPK1 3362/4885NPSR1 2878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.