SCHEMBL1532973

SCHEMBL1532973

C=CC(=O)OCCCCCCOc1ccc(-c2ccccc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.68
HDAC1 Q13547 12/20 0.58
HDAC2 Q92769 12/20 0.58
HDAC3 O15379 11/20 0.58
HDAC4 P56524 11/20 0.58
HDAC7 Q8WUI4 11/20 0.58
HDAC10 Q969S8 11/20 0.58
HDAC11 Q96DB2 11/20 0.58
HDAC8 Q9BY41 11/20 0.58
HDAC6 Q9UBN7 11/20 0.58
HDAC9 Q9UKV0 11/20 0.58
HDAC5 Q9UQL6 11/20 0.58
ALDH1A1 P00352 1/20 0.56
CYP3A4 P08684 1/20 0.56
TSHR P16473 1/20 0.56
HTT P42858 1/20 0.51
HRH3 Q9Y5N1 4/20 0.50
KCNH2 Q12809 2/20 0.50
HRH4 Q9H3N8 2/20 0.50
HRH1 P35367 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16893927 1.00 THRB (0.68) THRBHDAC1HDAC2HDAC3HDAC4
SCHEMBL16893714 1.00 THRB (0.68) THRBHDAC1HDAC2HDAC3HDAC4
SCHEMBL26981904 1.00 THRB (0.68) THRBHDAC1HDAC2HDAC3HDAC4
SCHEMBL16893846 1.00 THRB (0.68) THRBHDAC1HDAC2HDAC3HDAC4
SCHEMBL16893840 1.00 THRB (0.68) THRBHDAC1HDAC2HDAC3HDAC4
SCHEMBL16893915 1.00 THRB (0.68) THRBHDAC1HDAC2HDAC3HDAC4
SCHEMBL16893724 0.98 THRB (0.69) THRBHDAC1HDAC2HDAC3HDAC4
SCHEMBL16893759 0.95 THRB (0.69) THRBHDAC1HDAC2HDAC3HDAC4
SCHEMBL14907526 0.94 TSHR (0.63) THRBHDAC1HDAC2HDAC3HDAC4
SCHEMBL12172633 0.94 TSHR (0.63) THRBHDAC1HDAC2HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11952450-B2 Compound for encapsulation film and composition thereof, and film, organic light-emitting device and encapsulation method JILIN OLED OPTICAL AND ELECTRONIC MATERIALS CO., LTD. (CN) 2024-04-09 US claimed
US-20220259352-A1 Compound for encapsulation film and composition thereof, and film, organic light-emitting device and encapsulation method JILIN OLED OPTICAL AND ELECTRONIC MATERIALS CO., LTD. (CN) 2022-08-18 US claimed
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 US disclosed
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 US disclosed
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 US disclosed
US-11952450-B2 Compound for encapsulation film and composition thereof, and film, organic light-emitting device and encapsulation method JILIN OLED OPTICAL AND ELECTRONIC MATERIALS CO., LTD. (CN) 2024-04-09 US disclosed
EP-4299283-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE Tosoh Corporation (JP) 2024-01-03 EP disclosed
CN-110357916-B Compound for packaging film, composition and film thereof, organic light-emitting device and packaging method 吉林奥来德光电材料股份有限公司 2020-09-08 CN disclosed
US-10670796-B2 Organic-inorganic hybrid composition, optical member and optical device prepared using the same LMS CO., LTD. (KR) 2020-06-02 US disclosed
CN-111153922-A Compound, composition for packaging photoelectric device, preparation method, packaging film, electronic device and packaging method 吉林奥来德光电材料股份有限公司 2020-05-15 CN disclosed
WO-2019151549-A1 HIGH REFRACTIVE INDEX ACRYLIC MONOMER AND PHOTOCURABLE COMPOSITION USING SAME 에스엠에스주식회사 2019-08-08 WO disclosed
US-20110181826-A1 RADIAL-SHAPED LIQUID CRYSTAL COMPOUND, AND OPTICAL FILM AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2011-07-28 US disclosed
US-20110121281-A1 ORGANIC TRANSISTOR AND METHOD FOR PRODUCING THE SAME DIC CORPORATION (JP) 2011-05-26 US disclosed
EP-2312637-A1 ORGANIC TRANSISTOR AND METHOD FOR MANUFACTURING THE SAME DIC Corporation (JP) 2011-04-20 EP disclosed
EP-1754768-B1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND OPTICALLY ANISOTROPIC BODY DAINIPPON INK & CHEMICALS (JP) 2011-03-30 EP disclosed
CN-100572502-C Polymerizable liquid crystal composition and optically anisotropic body DAINIPPON INK & CHEMICALS (JP) 2009-12-23 CN disclosed
US-7449223-B2 containing an additive that improves the level of defects in the vicinity of the air interface for an optically anisotropic medium that exhibits either tilted alignment or horizontal alignment DAINIPPON INK AND CHEMICALS, INC. (JP) 2008-11-11 US disclosed
US-20070170394-A1 Polymerizable liquid crystal composition and optically anisotropic medium DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-07-26 US disclosed
CN-1961057-A Polymerizable liquid crystal composition and optical anisotropic object DAINIPPON INK & CHEMICALS (JP) 2007-05-09 CN disclosed
EP-1754768-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND OPTICALLY ANISOTROPIC BODY Dainippon Ink and Chemicals, Incorporated (JP) 2007-02-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220259352-A1 Compound for encapsulation film and composition thereof, and film, organic light-emitting device and encapsulation method AOX1, LOXL1, SEM1 THRB 4217/4885HDAC1 3554/4885HDAC2 4474/4885
US-20110181826-A1 RADIAL-SHAPED LIQUID CRYSTAL COMPOUND, AND OPTICAL FILM AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING THE SAME CXCR1, NLRP1, RCC1 THRB 4255/4885HDAC1 3924/4885HDAC2 4416/4885
US-11952450-B2 Compound for encapsulation film and composition thereof, and film, organic light-emitting device and encapsulation method TTPA, LOX, AOX1 THRB 4377/4885HDAC1 4520/4885HDAC2 4753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.