Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330816 | 0.83 | MAPT (0.54) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL2559653 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1XDHPKM | |
| SCHEMBL15332330 | 0.81 | NPC1 (0.44) | ALDH1A1KMT2AMEN1PKMMAPT | |
| SCHEMBL15331047 | 0.78 | NPC1 (0.42) | ALDH1A1KMT2AMEN1PKMMAPT | |
| SCHEMBL15330970 | 0.78 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL3321144 | 0.78 | RAB9A (0.49) | ALDH1A1KMT2AMEN1MAPTPTGS2 | |
| SCHEMBL15332658 | 0.75 | PKM (0.47) | ALDH1A1KMT2APKMMAPTERN1 | |
| SCHEMBL29950997 | 0.75 | HIF1A (0.45) | KMT2AMEN1XDHMAPTPTGS2 | |
| SCHEMBL15331298 | 0.74 | LMNA (0.43) | ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL15331175 | 0.73 | MAPT (0.46) | ALDH1A1KMT2AMEN1PKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |