Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | FABP3 | P05413 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 12/20 | 0.43 |
| ▸ | PLAT | P00750 | 4/20 | 0.43 |
| ▸ | F10 | P00742 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.39 |
| ▸ | HPN | P05981 | 1/20 | 0.39 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 8/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19400681 | 1.00 | NR3C1 (0.47) | NR3C1FABP3FABP4FABP5PLAU | |
| SCHEMBL15841579 | 1.00 | NR3C1 (0.47) | NR3C1FABP3FABP4FABP5PLAU | |
| SCHEMBL15043438 | 1.00 | NR3C1 (0.47) | NR3C1FABP3FABP4FABP5PLAU | |
| SCHEMBL2240939 | 1.00 | NR3C1 (0.47) | NR3C1FABP3FABP4FABP5PLAU | |
| SCHEMBL810279 | 1.00 | NR3C1 (0.47) | NR3C1FABP3FABP4FABP5PLAU | |
| SCHEMBL15364300 | 1.00 | NR3C1 (0.47) | NR3C1FABP3FABP4FABP5PLAU | |
| SCHEMBL17617915 | 1.00 | NR3C1 (0.47) | NR3C1FABP3FABP4FABP5PLAU | |
| Benzene SCHEMBL4859250 | 0.99 | NR3C1 (0.46) | NR3C1FABP3FABP4FABP5PLAU | |
| Benzene SCHEMBL4859285 | 0.99 | NR3C1 (0.46) | NR3C1FABP3FABP4FABP5PLAU | |
| Hexamethylbenzene SCHEMBL4855077 | 0.95 | NR3C1 (0.44) | NR3C1FABP3FABP4FABP5PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160002142-A1 | PHENYLGLYOXYLIC ACID DERIVATIVES AND THEIR PREPARATION AND USE | TRANSTECH PHARMA, INC. | 2016-01-07 | — | — | US | claimed |
| US-20130296599-A1 | PHENYLGLYOXYLIC ACID DERIVATIVES AND THEIR PREPARATION AND USE | VTV THERAPEUTICS LLC | 2013-11-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160002142-A1 | PHENYLGLYOXYLIC ACID DERIVATIVES AND THEIR PREPARATION AND USE | HPD, GRHPR, AGXT | NR3C1 1719/4885FABP3 2694/4885FABP4 2067/4885 |
| US-20130296599-A1 | PHENYLGLYOXYLIC ACID DERIVATIVES AND THEIR PREPARATION AND USE | HPD, GRHPR, AGXT | NR3C1 1719/4885FABP3 2694/4885FABP4 2067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.