Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | FABP3 | P05413 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 12/20 | 0.43 |
| ▸ | PLAT | P00750 | 4/20 | 0.43 |
| ▸ | F10 | P00742 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.39 |
| ▸ | HPN | P05981 | 1/20 | 0.39 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 8/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15364299 | 1.00 | NR3C1 (0.47) | NR3C1FABP3FABP4FABP5PLAU | |
| SCHEMBL19400681 | 1.00 | NR3C1 (0.47) | NR3C1FABP3FABP4FABP5PLAU | |
| SCHEMBL15841579 | 1.00 | NR3C1 (0.47) | NR3C1FABP3FABP4FABP5PLAU | |
| SCHEMBL15043438 | 1.00 | NR3C1 (0.47) | NR3C1FABP3FABP4FABP5PLAU | |
| SCHEMBL2240939 | 1.00 | NR3C1 (0.47) | NR3C1FABP3FABP4FABP5PLAU | |
| SCHEMBL15364300 | 1.00 | NR3C1 (0.47) | NR3C1FABP3FABP4FABP5PLAU | |
| SCHEMBL17617915 | 1.00 | NR3C1 (0.47) | NR3C1FABP3FABP4FABP5PLAU | |
| Benzene SCHEMBL4859250 | 0.99 | NR3C1 (0.46) | NR3C1FABP3FABP4FABP5PLAU | |
| Benzene SCHEMBL4859285 | 0.99 | NR3C1 (0.46) | NR3C1FABP3FABP4FABP5PLAU | |
| Hexamethylbenzene SCHEMBL4855077 | 0.95 | NR3C1 (0.44) | NR3C1FABP3FABP4FABP5PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2868659-B1 | Method for producing optically active naphthalene compound | MITSUBISHI TANABE PHARMA CORP (JP) | 2016-05-04 | — | — | EP | claimed |
| US-9181217-B2 | Method for producing optically active naphthalene compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-11-10 | — | — | US | claimed |
| US-20150152082-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE NAPHTHALENE COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-06-04 | — | — | US | claimed |
| EP-2868659-A1 | Method for producing optically active naphthalene compound | Mitsubishi Tanabe Pharma Corporation (JP) | 2015-05-06 | — | — | EP | claimed |
| EP-2749558-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE NAPHTHALENE COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2014-07-02 | — | — | EP | claimed |
| US-20130237708-A1 | Optically Active Cyclic Alcohol Compound And Method For Preparing The Same | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-09-12 | — | — | US | claimed |
| EP-1944291-B1 | Optically active cyclic alcohol compound and method for producing same | MITSUBISHI TANABE PHARMA CORP (JP) | 2012-06-13 | — | — | EP | claimed |
| US-20100152451-A1 | OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PREPARING THE SAME | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-06-17 | — | — | US | claimed |
| EP-1944291-A1 | OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PRODUCING SAME | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-07-16 | — | — | EP | claimed |
| EP-2399895-B1 | Process for producing optically active aliphatic fluoroalcohol | KANTO KAGAKU (JP) | 2018-08-08 | — | — | EP | disclosed |
| EP-2773611-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE -HYDROXY- -AMINOCARBOXYLIC ACID ESTER | TAKASAGO PERFUMERY CO LTD (JP) | 2017-01-11 | — | — | EP | disclosed |
| US-9468919-B2 | Ruthenium-diamine complexes and method for producing optically active compounds | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2016-10-18 | — | — | US | disclosed |
| EP-2868659-B1 | Method for producing optically active naphthalene compound | MITSUBISHI TANABE PHARMA CORP (JP) | 2016-05-04 | — | — | EP | disclosed |
| US-20160067696-A1 | RUTHENIUM-DIAMINE COMPLEXES AND METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUNDS | TAKASAGO PERFUMERY CO LTD (JP) | 2016-03-10 | — | — | US | disclosed |
| US-20050107621-A1 | 3-Hydroxy-3-(2-thienyl) propionamides and production method thereof, and production method of 3-amino-1-(2-thienyl)-1-propanols using the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2005-05-19 | — | — | US | disclosed |
| US-20050101787-A1 | Process for preparing optically active nitro compounds and cyano compounds | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2005-05-12 | — | — | US | disclosed |
| EP-1486493-A1 | 3-HYDROXY-3-(2-THIENYL)PROPIONAMIDE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING 3-AMINO-1-(2-THIENYL)-1-PROPANOL COMPOUND THEREFROM | Mitsubishi Chemical Corporation (JP) | 2004-12-15 | — | — | EP | disclosed |
| US-6686505-B2 | HYDROGENATION OF NITRO KETONE OR CYANO KETONE IN PRESENCE OF TRANSITION METAL COMPOUND CATALYST; AMINATION | KANTO KAGUKU KABUSHIKI KAISHA (JP) | 2004-02-03 | — | — | US | disclosed |
| US-20030171592-A1 | Process for producing optically active amino alcohols and intermediates therefore | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2003-09-11 | — | — | US | disclosed |
| EP-1308435-A2 | Process for producing optically active amino alcohols | Kanto Kagaku Kabushiki Kaisha (JP) | 2003-05-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107621-A1 | 3-Hydroxy-3-(2-thienyl) propionamides and production method thereof, and production method of 3-amino-1-(2-thienyl)-1-propanols using the same | APEH, AADAC, KMO | NR3C1 2924/4885FABP3 2834/4885FABP4 1724/4885 |
| US-20030171592-A1 | Process for producing optically active amino alcohols and intermediates therefore | ADH1A, NOS1, ADH5 | NR3C1 3605/4885FABP3 3021/4885FABP4 3918/4885 |
| US-20150152082-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE NAPHTHALENE COMPOUND | HRH1, HRH4, RB1 | NR3C1 79/4885FABP3 4854/4885FABP4 4390/4885 |
| US-20100152451-A1 | OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PREPARING THE SAME | ADH1C, ADH1A, ADH5 | NR3C1 1177/4885FABP3 3756/4885FABP4 2837/4885 |
| US-20050101787-A1 | Process for preparing optically active nitro compounds and cyano compounds | NOS1, NOS2, NOX1 | NR3C1 3425/4885FABP3 4821/4885FABP4 4828/4885 |
| US-20130237708-A1 | Optically Active Cyclic Alcohol Compound And Method For Preparing The Same | ADH1C, ADH1A, ADH5 | NR3C1 1177/4885FABP3 3756/4885FABP4 2837/4885 |
| US-20160067696-A1 | RUTHENIUM-DIAMINE COMPLEXES AND METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUNDS | ADH1A, ADH1C, ADH5 | NR3C1 2628/4885FABP3 4843/4885FABP4 4668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.