Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | FABP3 | P05413 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 12/20 | 0.43 |
| ▸ | PLAT | P00750 | 4/20 | 0.43 |
| ▸ | F10 | P00742 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.39 |
| ▸ | HPN | P05981 | 1/20 | 0.39 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 8/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15364299 | 1.00 | NR3C1 (0.47) | NR3C1FABP3FABP4FABP5PLAU | |
| SCHEMBL19400681 | 1.00 | NR3C1 (0.47) | NR3C1FABP3FABP4FABP5PLAU | |
| SCHEMBL15841579 | 1.00 | NR3C1 (0.47) | NR3C1FABP3FABP4FABP5PLAU | |
| SCHEMBL15043438 | 1.00 | NR3C1 (0.47) | NR3C1FABP3FABP4FABP5PLAU | |
| SCHEMBL810279 | 1.00 | NR3C1 (0.47) | NR3C1FABP3FABP4FABP5PLAU | |
| SCHEMBL15364300 | 1.00 | NR3C1 (0.47) | NR3C1FABP3FABP4FABP5PLAU | |
| SCHEMBL17617915 | 1.00 | NR3C1 (0.47) | NR3C1FABP3FABP4FABP5PLAU | |
| Benzene SCHEMBL4859250 | 0.99 | NR3C1 (0.46) | NR3C1FABP3FABP4FABP5PLAU | |
| Benzene SCHEMBL4859285 | 0.99 | NR3C1 (0.46) | NR3C1FABP3FABP4FABP5PLAU | |
| Hexamethylbenzene SCHEMBL4855077 | 0.95 | NR3C1 (0.44) | NR3C1FABP3FABP4FABP5PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130237708-A1 | Optically Active Cyclic Alcohol Compound And Method For Preparing The Same | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-09-12 | — | — | US | claimed |
| EP-1944291-B1 | Optically active cyclic alcohol compound and method for producing same | MITSUBISHI TANABE PHARMA CORP (JP) | 2012-06-13 | — | — | EP | claimed |
| US-20100152451-A1 | OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PREPARING THE SAME | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-06-17 | — | — | US | claimed |
| EP-1944291-A1 | OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PRODUCING SAME | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-07-16 | — | — | EP | claimed |
| US-20230398529-A1 | ASYMMETRIC TRANSFER HYDROGENATION OF 2-ARYL SUBSTITUTED BICYCLIC PYRIDINE KETONES IN PRESENCE OF A CHIRAL RUTHENIUM CATALYST | BAYER AKTIENGESELLSCHAFT (DE) | 2023-12-14 | — | — | US | disclosed |
| EP-3194364-B1 | METHODS FOR PREPARATION OF AMINE COMPOUNDS AND INTERMEDIATES THEREOF | JOHNSON MATTHEY PLC (GB) | 2020-11-04 | — | — | EP | disclosed |
| EP-2773611-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE -HYDROXY- -AMINOCARBOXYLIC ACID ESTER | TAKASAGO PERFUMERY CO LTD (JP) | 2017-01-11 | — | — | EP | disclosed |
| US-20160002142-A1 | PHENYLGLYOXYLIC ACID DERIVATIVES AND THEIR PREPARATION AND USE | TRANSTECH PHARMA, INC. | 2016-01-07 | — | — | US | disclosed |
| US-9162963-B2 | Phenylglyoxylic acid derivatives and their preparation and use | VTV THERAPEUTICS LLC (US) | 2015-10-20 | — | — | US | disclosed |
| US-20140296562-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE BETA-HYDROXY-ALPHA-AMINOCARBOXYLIC ACID ESTER | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-10-02 | — | — | US | disclosed |
| US-20140296562-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE BETA-HYDROXY-ALPHA-AMINOCARBOXYLIC ACID ESTER | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-10-02 | — | — | US | disclosed |
| US-8754221-B2 | Optically active cyclic alcohol compound and method for preparing the same | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2014-06-17 | — | — | US | disclosed |
| WO-2013065867-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE β-HYDROXY-α-AMINOCARBOXYLIC ACID ESTER | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-05-10 | — | — | WO | disclosed |
| EP-1944291-B1 | Optically active cyclic alcohol compound and method for producing same | MITSUBISHI TANABE PHARMA CORP (JP) | 2012-06-13 | — | — | EP | disclosed |
| EP-2371820-A1 | Optically active cyclic alcohol compound and method for preparing the same | Mitsubishi Tanabe Pharma Corporation (JP) | 2011-10-05 | — | — | EP | disclosed |
| US-20110196157-A1 | OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PREPARING THE SAME | MITSUBISHI TANABE PHARMA CORPORATION | 2011-08-11 | — | — | US | disclosed |
| US-7989627-B2 | Optically active cyclic alcohol compound and method for preparing the same | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-08-02 | — | — | US | disclosed |
| US-20100152451-A1 | OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PREPARING THE SAME | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-06-17 | — | — | US | disclosed |
| EP-1944291-A1 | OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PRODUCING SAME | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-07-16 | — | — | EP | disclosed |
| US-20050101787-A1 | Process for preparing optically active nitro compounds and cyano compounds | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2005-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160002142-A1 | PHENYLGLYOXYLIC ACID DERIVATIVES AND THEIR PREPARATION AND USE | HPD, GRHPR, AGXT | NR3C1 1719/4885FABP3 2694/4885FABP4 2067/4885 |
| US-20140296562-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE BETA-HYDROXY-ALPHA-AMINOCARBOXYLIC ACID ESTER | ALAD, AADAT, ALDH7A1 | NR3C1 1651/4885FABP3 1169/4885FABP4 1155/4885 |
| US-20230398529-A1 | ASYMMETRIC TRANSFER HYDROGENATION OF 2-ARYL SUBSTITUTED BICYCLIC PYRIDINE KETONES IN PRESENCE OF A CHIRAL RUTHENIUM CATALYST | ADH5, ADH1A, ADH1C | NR3C1 3176/4885FABP3 3896/4885FABP4 3387/4885 |
| US-20110196157-A1 | OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PREPARING THE SAME | ADH1C, ADH1A, ADH5 | NR3C1 1177/4885FABP3 3756/4885FABP4 2837/4885 |
| US-20100152451-A1 | OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PREPARING THE SAME | ADH1C, ADH1A, ADH5 | NR3C1 1177/4885FABP3 3756/4885FABP4 2837/4885 |
| US-20050101787-A1 | Process for preparing optically active nitro compounds and cyano compounds | NOS1, NOS2, NOX1 | NR3C1 3425/4885FABP3 4821/4885FABP4 4828/4885 |
| US-20130237708-A1 | Optically Active Cyclic Alcohol Compound And Method For Preparing The Same | ADH1C, ADH1A, ADH5 | NR3C1 1177/4885FABP3 3756/4885FABP4 2837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.