SCHEMBL15375445

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15375398	0.87	ACHE (0.34)	NISCHLMNAKMT2AMEN1CYP1A2
	SCHEMBL15375550	0.86	SGMS2 (0.41)	NISCHSGMS2ALDH1A1LMNAADRB2
	SCHEMBL28038432	0.86	ALOX15 (0.44)	SGMS2ALDH1A1LMNAADRB2ADRB1
	SCHEMBL15375461	0.86	MAPT (0.46)	NISCHSGMS2ALDH1A1LMNAADRB2
	SCHEMBL15375387	0.86	GLRA1 (0.37)	SGMS2LMNACYP1A2CYP3A4FABP4
	SCHEMBL1900216	0.86	ALOX15 (0.44)	SGMS2ALDH1A1LMNAADRB2ADRB1
	SCHEMBL15375378	0.82	RXRA (0.44)	NISCHSGMS2ALDH1A1LMNACYP1A2
	SCHEMBL15375379	0.82	SGMS2 (0.38)	SGMS2ALDH1A1LMNACYP1A2CYP2C9
	SCHEMBL28810581	0.81	RXRA (0.41)	ALDH1A1LMNAKMT2AMEN1KDM4E
	SCHEMBL15375483	0.81	RXRA (0.41)	ALDH1A1LMNAKMT2AMEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.