Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | ERN1 | O75460 | 8/20 | 0.48 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.45 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1537555 | 0.94 | ALDH1A1 (0.68) | ALDH1A1ERN1EGFRKDM4ETSHR | |
| SCHEMBL15160947 | 0.84 | ALDH1A1 (0.79) | ALDH1A1ERN1EGFRTSHR | |
| SCHEMBL15008457 | 0.84 | RXRA (0.61) | ERN1RXRAEGFRKDM4EKDM6B | |
| SCHEMBL14577650 | 0.84 | ALDH1A1 (0.56) | ALDH1A1ERN1KDM4EKDM6BKDM5C | |
| SCHEMBL1495508 | 0.83 | DHODH (0.57) | ALDH1A1RXRADHODHEGFRKDM4E | |
| SCHEMBL3049378 | 0.82 | DHODH (0.59) | DHODHEGFRTSHR | |
| SCHEMBL2389679 | 0.82 | ALDH1A1 (0.89) | ALDH1A1ERN1EGFRTSHR | |
| SCHEMBL2561821 | 0.82 | RXRA (0.64) | ALDH1A1ERN1TRIM24TRIM33RXRA | |
| SCHEMBL184501 | 0.81 | KDM4E (0.55) | ERN1RXRADHODHEGFRKDM4E | |
| SCHEMBL10068712 | 0.80 | ALDH1A1 (0.53) | ALDH1A1ERN1TRIM24TRIM33EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110064694-A1 | ANTI-HEPATITIS C ACTIVITY OF MESO-TETRAKIS-PORPHYRIN ANALOGUES | YALE UNIVERSITY (US) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110064694-A1 | ANTI-HEPATITIS C ACTIVITY OF MESO-TETRAKIS-PORPHYRIN ANALOGUES | HAVCR2, HCCS, HMBS | ALDH1A1 3535/4885ERN1 3075/4885TRIM24 1222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.