SCHEMBL2389679

SCHEMBL2389679

COC(=O)c1ccc(-c2ccc(C=O)cc2)cc1

nearest known ligand 0.89

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.89
ERN1 O75460 4/20 0.61
CA1 P00915 5/20 0.54
CA2 P00918 5/20 0.54
CA12 O43570 4/20 0.54
CA9 Q16790 4/20 0.54
CA14 Q9ULX7 4/20 0.54
TDP1 Q9NUW8 1/20 0.53
CA7 P43166 1/20 0.53
PTPN1 P18031 2/20 0.51
MAPT P10636 2/20 0.51
TSHR P16473 1/20 0.50
GRIN2D O15399 1/20 0.49
GRIN3B O60391 1/20 0.49
GRIN1 Q05586 1/20 0.49
GRIN2A Q12879 1/20 0.49
GRIN2B Q13224 1/20 0.49
GRIN2C Q14957 1/20 0.49
GRIN3A Q8TCU5 1/20 0.49
EGFR P00533 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15160947 0.95 ALDH1A1 (0.79) ALDH1A1ERN1CA1CA2CA12
SCHEMBL28033399 0.94 ALDH1A1 (1.00) ALDH1A1ERN1CA1CA2CA12
SCHEMBL79533 0.94 ALDH1A1 (1.00) ALDH1A1ERN1CA1CA2CA12
SCHEMBL14789231 0.89 ALDH1A1 (0.89) ALDH1A1ERN1CA1CA2CA12
SCHEMBL21433629 0.87 ALDH1A1 (0.68) ALDH1A1ERN1CA1CA2CA12
SCHEMBL1537555 0.87 ALDH1A1 (0.68) ALDH1A1ERN1CA1CA2CA12
SCHEMBL19387238 0.85 CA1 (0.70) ALDH1A1ERN1CA1CA2CA12
Biphenyl Dimethyl Dicarboxylate SCHEMBL68521 0.85 CA1 (0.70) ALDH1A1ERN1CA1CA2CA12
SCHEMBL13244579 0.85 ALDH1A1 (0.82) ALDH1A1ERN1CA1CA2CA12
SCHEMBL4598157 0.85 ALDH1A1 (0.82) ALDH1A1CA1CA2CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078105-A1 Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors ORSOBIO INC (US) 2026-03-19 US disclosed
US-12379315-B2 Nitrodiarylethenes as fluorescence quenchers for nucleic acid probes ELITECHGROUP MDX LLC (US) 2025-08-05 US disclosed
WO-2024098039-A2 POTENT ASGPR-BINDING HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS AVILAR THERAPEUTICS, INC. (US) 2024-05-10 WO disclosed
CN-114149389-B Preparation method of naphthoquinone epoxy compound 万华化学集团股份有限公司 2023-09-19 CN disclosed
US-20220119424-A1 NITRODIARYLETHENES AS FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES ELITechGroup MDX, LLC (US) 2022-04-21 US disclosed
EP-3327001-B1 NOVEL COMPOUND HAVING BLT INHIBITORY ACTIVITY AND COMPOSITION, FOR PREVENTING OR TREATING INFLAMMATORY DISEASES, COMPRISING SAME AS ACTIVE INGREDIENT UNIV DONGGUK IND ACAD COOP (KR) 2022-04-13 EP disclosed
CN-114149389-A Preparation method of naphthoquinone epoxy compound 万华化学集团股份有限公司 2022-03-08 CN disclosed
US-11242554-B2 Nitrodiarylethenes as fluorescence quenchers for nucleic acid probes ELITECHGROUP, INC. (US) 2022-02-08 US disclosed
CN-108349875-B Compound having BLT inhibitory activity and composition for preventing or treating inflammatory disease comprising the same as active ingredient 东国大学校产学协力团 2021-08-27 CN disclosed
US-20200299755-A1 NITRODIARYLETHENES AS FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES ELITECHGROUP, INC. (US) 2020-09-24 US disclosed
US-20130023541-A1 VOLTAGE-GATED SODIUM CHANNEL BLOCKERS GLAXO GROUP LIMITED 2013-01-24 US disclosed
US-8343967-B2 Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases ABBOTT LABORATORIES (US) 2013-01-01 US disclosed
US-20120214796-A1 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES ABBVIE INC. 2012-08-23 US disclosed
US-8188077-B2 Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases ABBOTT LABORATORIES (US) 2012-05-29 US disclosed
WO-2011119345-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES ABBOTT LABORATORIES (US) 2011-09-29 WO disclosed
US-20110237553-A1 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES ABBOTT LABORATORIES (US) 2011-09-29 US disclosed
US-20080076762-A1 Novel 4-Aminopiperidine Derivatives ACTELION PHARMACEUTICALS LTD. (CH) 2008-03-27 US disclosed
US-20040006141-A1 Amidocarboxylic acid compounds SANKYO COMPANY, LTD (JP) 2004-01-08 US disclosed
US-6528525-B1 Amidocarboxylic acid derivatives SANKYO COMPANY, LIMITED (JP) 2003-03-04 US disclosed
EP-1026149-A1 AMIDOCARBOXYLIC ACID DERIVATIVES Sankyo Company Limited (JP) 2000-08-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078105-A1 Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors CPT1B, CBR1, MUSK ALDH1A1 290/4885ERN1 3918/4885CA1 1765/4885
US-20220119424-A1 NITRODIARYLETHENES AS FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES DNTT, NME2, DUT ALDH1A1 640/4885ERN1 1805/4885CA1 3978/4885
US-20200299755-A1 NITRODIARYLETHENES AS FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES DNTT, NME2, DUT ALDH1A1 640/4885ERN1 1805/4885CA1 3978/4885
US-20130023541-A1 VOLTAGE-GATED SODIUM CHANNEL BLOCKERS KCNB1, KCNB2, SCNN1B ALDH1A1 2656/4885ERN1 4453/4885CA1 2167/4885
US-11242554-B2 Nitrodiarylethenes as fluorescence quenchers for nucleic acid probes DNTT, NME2, DUT ALDH1A1 640/4885ERN1 1805/4885CA1 3978/4885
US-20120214796-A1 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES BCL2, BAX, BCL3 ALDH1A1 4257/4885ERN1 1022/4885CA1 1290/4885
US-20040006141-A1 Amidocarboxylic acid compounds NR1H2, AGK, APOL1 ALDH1A1 3508/4885ERN1 2053/4885CA1 3246/4885
US-20110237553-A1 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES BCL2, BAX, BCL3 ALDH1A1 4257/4885ERN1 1022/4885CA1 1290/4885
US-12379315-B2 Nitrodiarylethenes as fluorescence quenchers for nucleic acid probes DNTT, NME2, DUT ALDH1A1 640/4885ERN1 1805/4885CA1 3978/4885
US-20080076762-A1 Novel 4-Aminopiperidine Derivatives METAP1, DNPEP, PEPD ALDH1A1 1303/4885ERN1 2794/4885CA1 1944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.