Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15375797 | 0.86 | CNR1 (0.61) | CNR2CNR1 | |
| SCHEMBL10666370 | 0.85 | CNR1 (0.79) | CNR2CNR1 | |
| SCHEMBL6324883 | 0.84 | CNR2 (0.71) | CNR2CNR1 | |
| SCHEMBL9661973 | 0.81 | CNR2 (0.65) | CNR2CNR1 | |
| SCHEMBL18919068 | 0.81 | CNR2 (0.51) | CNR2CNR1 | |
| SCHEMBL18919067 | 0.81 | CNR2 (0.51) | CNR2CNR1 | |
| SCHEMBL15142793 | 0.81 | CNR1 (0.80) | CNR2CNR1 | |
| SCHEMBL2148937 | 0.79 | ALDH1A1 (0.47) | CNR2CNR1 | |
| Hydrochloric Acid SCHEMBL9691201 | 0.79 | CNR1 (0.77) | CNR2CNR1 | |
| SCHEMBL30353008 | 0.79 | CNR1 (0.74) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170065602-A1 | COMPOUNDS WITH TRPV4 ACTIVITY, COMPOSITIONS AND ASSOCIATED METHODS THEREOF | THE UNIVERSITY OF UTAH | 2017-03-09 | — | — | US | disclosed |
| US-20170065602-A1 | COMPOUNDS WITH TRPV4 ACTIVITY, COMPOSITIONS AND ASSOCIATED METHODS THEREOF | THE UNIVERSITY OF UTAH | 2017-03-09 | — | — | US | disclosed |
| US-20170065602-A1 | COMPOUNDS WITH TRPV4 ACTIVITY, COMPOSITIONS AND ASSOCIATED METHODS THEREOF | THE UNIVERSITY OF UTAH | 2017-03-09 | — | — | US | disclosed |
| US-20150133411-A1 | COMPOUNDS WITH TRPV4 ACTIVITY, COMPOSITIONS AND ASSOCIATED METHODS THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-05-14 | — | — | US | disclosed |
| US-20150133411-A1 | COMPOUNDS WITH TRPV4 ACTIVITY, COMPOSITIONS AND ASSOCIATED METHODS THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-05-14 | — | — | US | disclosed |
| US-20150133411-A1 | COMPOUNDS WITH TRPV4 ACTIVITY, COMPOSITIONS AND ASSOCIATED METHODS THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-05-14 | — | — | US | disclosed |
| US-20130303539-A1 | COMPOUNDS WITH TRPV4 ACTIVITY, COMPOSITIONS AND ASSOCIATED METHODS THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-11-14 | — | — | US | disclosed |
| US-20130303539-A1 | COMPOUNDS WITH TRPV4 ACTIVITY, COMPOSITIONS AND ASSOCIATED METHODS THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-11-14 | — | — | US | disclosed |
| US-20130303539-A1 | COMPOUNDS WITH TRPV4 ACTIVITY, COMPOSITIONS AND ASSOCIATED METHODS THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133411-A1 | COMPOUNDS WITH TRPV4 ACTIVITY, COMPOSITIONS AND ASSOCIATED METHODS THEREOF | TRPV4, TRPV3, TRPV5 | CNR2 114/4885CNR1 271/4885 |
| US-20130303539-A1 | COMPOUNDS WITH TRPV4 ACTIVITY, COMPOSITIONS AND ASSOCIATED METHODS THEREOF | TRPV4, TRPV3, TRPV2 | CNR2 282/4885CNR1 589/4885 |
| US-20170065602-A1 | COMPOUNDS WITH TRPV4 ACTIVITY, COMPOSITIONS AND ASSOCIATED METHODS THEREOF | TRPV4, TRPV3, TRPV2 | CNR2 282/4885CNR1 589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.