Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 2/20 | 0.48 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.44 |
| ▸ | GABRE | P78334 | 1/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.44 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1173779 | 0.88 | PTPN1 (0.47) | HMGB1CXCL12HSD17B10HPGDALDH1A1 | |
| SCHEMBL18677494 | 0.85 | HMGB1 (0.47) | HMGB1CXCL12HSD17B10HPGDALDH1A1 | |
| SCHEMBL39260 | 0.83 | ALDH1A1 (0.48) | HMGB1CXCL12HSD17B10HPGDALDH1A1 | |
| SCHEMBL29284693 | 0.82 | KAT8 (0.53) | HSD17B10 | |
| SCHEMBL4959157 | 0.81 | PTPN1 (0.54) | HMGB1CXCL12HSD17B10HPGDALDH1A1 | |
| SCHEMBL19056973 | 0.81 | HMGB1 (0.44) | HMGB1CXCL12HSD17B10HPGDALDH1A1 | |
| SCHEMBL1641608 | 0.81 | HMGB1 (0.47) | HMGB1CXCL12HSD17B10HPGDALDH1A1 | |
| SCHEMBL28675093 | 0.81 | HMGB1 (0.47) | HMGB1CXCL12HSD17B10HPGDALDH1A1 | |
| SCHEMBL4116012 | 0.80 | GABRP (0.50) | HMGB1CXCL12HSD17B10HPGDALDH1A1 | |
| SCHEMBL2334997 | 0.80 | GABRP (0.55) | HMGB1CXCL12HSD17B10HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8802105-B2 | Antibacterial compositions | FORSYTH DENTAL INFIRMARY FOR CHILDREN (US) | 2014-08-12 | — | — | US | disclosed |
| US-20130303619-A1 | Antibacterial Compositions | FORSYTH DENTAL INFIRMARY FOR CHILDREN | 2013-11-14 | — | — | US | disclosed |