SCHEMBL39260

SCHEMBL39260

CCc1cc(O)cc(C(=O)O)c1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.48
HPGD P15428 1/20 0.48
HSD17B10 Q99714 1/20 0.48
PTPN1 P18031 9/20 0.46
PTPN11 Q06124 2/20 0.46
PTPN2 P17706 3/20 0.44
PTPN6 P29350 2/20 0.44
HMGB1 P09429 3/20 0.44
CXCL12 P48061 2/20 0.44
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA7 P43166 2/20 0.42
CA9 Q16790 2/20 0.42
CA14 Q9ULX7 2/20 0.42
ALOX5 P09917 1/20 0.42
PTGS2 P35354 1/20 0.42
GABRP O00591 1/20 0.42
GABRD O14764 1/20 0.42
GABRA1 P14867 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL40166 0.86 PTPN1 (0.59) ALDH1A1HPGDHSD17B10PTPN1PTPN11
SCHEMBL39883 0.83 GABRP (0.49) ALDH1A1HPGDHSD17B10PTPN1PTPN11
SCHEMBL15375739 0.83 HMGB1 (0.48) ALDH1A1HPGDHSD17B10PTPN1PTPN2
SCHEMBL30031871 0.82 ALDH1A1 (0.47) ALDH1A1HPGDHSD17B10PTPN1PTPN11
SCHEMBL30121105 0.82 ALDH1A1 (0.47) ALDH1A1HPGDHSD17B10PTPN1PTPN11
SCHEMBL23796482 0.82 ALDH1A1 (0.47) ALDH1A1HPGDHSD17B10PTPN1PTPN11
SCHEMBL1641608 0.82 HMGB1 (0.47) ALDH1A1HPGDHSD17B10PTPN1PTPN2
SCHEMBL4959157 0.82 PTPN1 (0.54) ALDH1A1HPGDHSD17B10PTPN1PTPN2
SCHEMBL39182 0.81 AKR1C2 (0.46) ALDH1A1HPGDHSD17B10PTPN1PTPN11
SCHEMBL1012355 0.81 ALOX5 (0.56) PTPN1PTPN11ALOX5PTGS2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9079989-B2 Charge control resin and manufacturing method of the same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-07-14 US disclosed
US-20150025213-A1 CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-01-22 US disclosed
US-8883946-B2 Charge control resin and manufacturing method of the same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2014-11-11 US disclosed
US-20140080989-A1 CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2014-03-20 US disclosed
EP-2584896-A2 HERBICIDAL COMPOSITIONS BASF SE (DE) 2013-05-01 EP disclosed
US-20130102463-A1 Herbicidal Compositions BASF SE (DE) 2013-04-25 US disclosed
WO-2011161105-A2 HERBICIDAL COMPOSITIONS BASF SE (DE) 2011-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130102463-A1 Herbicidal Compositions PPOX, PAOX, DDT ALDH1A1 347/4885HPGD 457/4885HSD17B10 283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.