Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | PGR | P06401 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | ELANE | P08246 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | FABP7 | O15540 | 4/20 | 0.47 |
| ▸ | FABP3 | P05413 | 4/20 | 0.47 |
| ▸ | FABP5 | Q01469 | 4/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31748924 | 1.00 | ALDH1A1 (0.60) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL10804065 | 0.87 | ELANE (0.53) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL12128703 | 0.86 | ALDH1A1 (0.57) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL7737365 | 0.86 | ALDH1A1 (0.57) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL29080821 | 0.85 | ELANE (0.54) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL11991243 | 0.83 | ALDH1A1 (0.54) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL7265465 | 0.83 | ALDH1A1 (0.54) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL16237325 | 0.83 | MAPT (0.53) | ALDH1A1HSD17B10ELANEKDM4E | |
| SCHEMBL29607284 | 0.82 | ELANE (0.74) | ALDH1A1ELANE | |
| SCHEMBL28221287 | 0.82 | ALDH1A1 (0.53) | ALDH1A1HSD17B10GAAPGRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12398154-B2 | Azaquinazoline pan-KRas inhibitors | Mirati Therapeutics, Inc. (US) | 2025-08-26 | — | — | US | disclosed |
| US-20230072276-A1 | Azaquinazoline pan-KRas inhibitors | Mirati Therapeutics, Inc. | 2023-03-09 | — | — | US | disclosed |
| US-10173980-B2 | Mixed disulfide conjugates of thienopyridine compounds and uses thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2019-01-08 | — | — | US | disclosed |
| US-20180155289-A1 | MIXED DISULFIDE CONJUGATES OF THIENOPYRIDINE COMPOUNDS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2018-06-07 | — | — | US | disclosed |
| US-20180155289-A1 | MIXED DISULFIDE CONJUGATES OF THIENOPYRIDINE COMPOUNDS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2018-06-07 | — | — | US | disclosed |
| EP-2157143-B1 | NONAQUEOUS INKJET INK COMPOSITION | DAINIPPON TORYO KK (JP) | 2017-03-08 | — | — | EP | disclosed |
| EP-2774923-B1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE | UNIV NAGOYA NAT UNIV CORP (JP) | 2016-05-18 | — | — | EP | disclosed |
| EP-2774923-B1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE | UNIV NAGOYA NAT UNIV CORP (JP) | 2016-05-18 | — | — | EP | disclosed |
| US-20160074853-A1 | LIGAND, NICKEL COMPLEX COMPRISING THE LIGAND, AND REACTION USING THE NICKEL COMPLEX | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2016-03-17 | — | — | US | disclosed |
| CN-104744186-A | Method for catalytic synthesis of biaryl compound by utilizing nickel catalyst | UNIV CAS | 2015-07-01 | — | — | CN | disclosed |
| US-20100056679-A1 | NON-AQUEOUS INK JET INK COMPOSITION | DAI NIPPON TORYO CO., LTD. (JP) | 2010-03-04 | — | — | US | disclosed |
| CN-101661233-A | Method for producing toner, two-component developer, developing device and image forming apparatus | SHARP KK | 2010-03-03 | — | — | CN | disclosed |
| EP-2157143-A1 | NONAQUEOUS INKJET INK COMPOSITION | Dai Nippon Toryo Co., Ltd. (JP) | 2010-02-24 | — | — | EP | disclosed |
| CN-101652436-A | Nonaqueous inkjet ink composition | DAINIPPON TORYO KK JP | 2010-02-17 | — | — | CN | disclosed |
| CN-100504625-C | Toner for electrostatic image development and process for preparing the same | SHARP KK (JP) | 2009-06-24 | — | — | CN | disclosed |
| US-7342016-B2 | Farnesyl protein transferase inhibitors as antitumor agents | SCHERING CORPORATION (US) | 2008-03-11 | — | — | US | disclosed |
| US-20070138139-A1 | METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE, ACID ETCHING RESISTANCE MATERIAL AND COPOLYMER | ASAKAWA KOJI | 2007-06-21 | — | — | US | disclosed |
| US-20070142592-A1 | METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE, ACID ETCHING RESISTANCE MATERIAL AND COPOLYMER | ASAKAWA KOJI | 2007-06-21 | — | — | US | disclosed |
| US-7208334-B2 | Method of manufacturing semiconductor device, acid etching resistance material and copolymer | KABUSHIKI KAISHA TOSHIBA (JP) | 2007-04-24 | — | — | US | disclosed |
| CN-1847988-A | Toner for electrostatic image development and process for preparing the same | SHARP KK (JP) | 2006-10-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160074853-A1 | LIGAND, NICKEL COMPLEX COMPRISING THE LIGAND, AND REACTION USING THE NICKEL COMPLEX | NISCH, DDT, TEC | ALDH1A1 2430/4885HSD17B10 2678/4885GAA 3088/4885 |
| US-10173980-B2 | Mixed disulfide conjugates of thienopyridine compounds and uses thereof | TST, TXN, TXNRD2 | ALDH1A1 218/4885HSD17B10 1284/4885GAA 3663/4885 |
| US-20180155289-A1 | MIXED DISULFIDE CONJUGATES OF THIENOPYRIDINE COMPOUNDS AND USES THEREOF | TST, TXN, TXNRD2 | ALDH1A1 218/4885HSD17B10 1284/4885GAA 3663/4885 |
| US-20230072276-A1 | Azaquinazoline pan-KRas inhibitors | KRAS, NRAS, HRAS | ALDH1A1 4127/4885HSD17B10 4758/4885GAA 3182/4885 |
| US-12398154-B2 | Azaquinazoline pan-KRas inhibitors | KRAS, NRAS, HRAS | ALDH1A1 4127/4885HSD17B10 4758/4885GAA 3182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.