SCHEMBL15399512

SCHEMBL15399512

NC(=S)N(C(=O)c1ccccc1)N1CCOCC1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PHGDH O43175 1/20 0.50
KMT2A Q03164 5/20 0.46
ALDH1A1 P00352 4/20 0.46
MAPT P10636 3/20 0.46
SMN1; SMN2 Q16637 6/20 0.45
LMNA P02545 1/20 0.45
HTT P42858 1/20 0.45
NPC1 O15118 4/20 0.44
RAB9A P51151 2/20 0.44
HPGD P15428 1/20 0.43
TSHR P16473 1/20 0.43
GAA P10253 2/20 0.41
FAAH O00519 1/20 0.41
MGLL Q99685 1/20 0.41
NCOA3 Q9Y6Q9 1/20 0.41
KDM4E B2RXH2 1/20 0.41
EPHX1 P07099 1/20 0.40
ATM Q13315 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28948313 0.76 TSHR (0.49) PHGDHKMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL7675958 0.76 SMN1; SMN2 (0.47) KMT2AALDH1A1MAPTSMN1; SMN2LMNA
SCHEMBL19207389 0.72 ALDH1A1 (0.44) PHGDHKMT2AALDH1A1MAPTLMNA
SCHEMBL27966258 0.71 LMNA (0.52) PHGDHKMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL28770204 0.70 SIGMAR1 (0.50) ALDH1A1MAPTTSHR
SCHEMBL11477756 0.70 ALDH1A1 (0.38) KMT2AALDH1A1MAPTLMNAHTT
SCHEMBL6267389 0.68 TSHR (0.50) ALDH1A1MAPTHPGDTSHRGAA
SCHEMBL5174220 0.68 HPGD (0.42) KMT2AALDH1A1MAPTSMN1; SMN2LMNA
SCHEMBL19357132 0.67 PHGDH (1.00) PHGDHKMT2AALDH1A1SMN1; SMN2LMNA
SCHEMBL8161183 0.67 ALDH1A1 (0.58) KMT2AALDH1A1MAPTSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112805345-A Two-part cyanoacrylate/free radically curable adhesive systems 汉高知识产权控股有限责任公司 2021-05-14 CN claimed
CN-112805345-B Two-part cyanoacrylate/free radical curable adhesive system 汉高股份有限及两合公司 2023-12-08 CN disclosed
CN-112566994-B Two-step adhesive system 汉高股份有限及两合公司 2023-08-04 CN disclosed
CN-110536941-B Adhesive composition 汉高知识产权控股有限责任公司 2022-04-19 CN disclosed
CN-112805345-A Two-part cyanoacrylate/free radically curable adhesive systems 汉高知识产权控股有限责任公司 2021-05-14 CN disclosed
CN-112566994-A Two-step adhesive system 汉高知识产权控股有限责任公司 2021-03-26 CN disclosed
US-10590311-B2 Accelerators for two part curable compositions Henkel IP & Holding GmbH (DE) 2020-03-17 US disclosed
CN-110536941-A Adhesive composition Henkel IP & Holding GmbH 2019-12-03 CN disclosed
CN-104395421-B Accelerating agent for two-step method adhesive composition 汉高知识产权控股有限责任公司 2018-05-08 CN disclosed
US-9371473-B2 Accelerators for two step adhesive systems Henkel IP & Holding GmbH (DE) 2016-06-21 US disclosed
US-9365750-B2 Accelerators for curable compositions Henkel IP & Holding GmbH (DE) 2016-06-14 US disclosed
EP-2866798-A1 ACCELERATORS FOR TWO PART CURABLE COMPOSITIONS Henkel IP & Holding GmbH (DE) 2015-05-06 EP disclosed
US-8986847-B2 Accelerator/oxidant/proton source combinations for two part curable compositions Henkel IP & Holding GmbH (DE) 2015-03-24 US disclosed
CN-104395421-A Accelerators for two step adhesive systems Henkel US IP LLC 2015-03-04 CN disclosed
WO-2014004309-A1 ACCELERATORS FOR TWO PART CURABLE COMPOSITIONS Henkel US IP LLC (US) 2014-01-03 WO disclosed
US-20140004366-A1 ACCELERATOR/OXIDANT/PROTON SOURCE COMBINATIONS FOR TWO PART CURABLE COMPOSITIONS HENKEL CORPORATION (US) 2014-01-02 US disclosed
US-20140004353-A1 ACCELERATORS FOR CURABLE COMPOSITIONS HENKEL IRELAND LIMITED (DE) 2014-01-02 US disclosed
US-20140004354-A1 ACCELERATORS FOR TWO PART CURABLE COMPOSITIONS HENKEL IRELAND LIMITED (DE) 2014-01-02 US disclosed
US-20140000807-A1 ACCELERATORS FOR TWO STEP ADHESIVE SYSTEMS HENKEL IRELAND LIMITED (DE) 2014-01-02 US disclosed