Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15399512 | 0.76 | PHGDH (0.50) | SMN1; SMN2ALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL1591508 | 0.68 | ALDH1A1 (0.88) | SMN1; SMN2ALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL29921739 | 0.68 | ALDH1A1 (0.88) | SMN1; SMN2ALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL8763794 | 0.68 | ALDH1A1 (0.88) | SMN1; SMN2ALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL11477756 | 0.67 | ALDH1A1 (0.38) | ALDH1A1HSD17B10MAPTKMT2AKDM4E | |
| SCHEMBL2153384 | 0.67 | KCNH2 (0.76) | SMN1; SMN2ALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL6267389 | 0.65 | TSHR (0.50) | ALDH1A1HPGDHSD17B10MAPTTSHR | |
| SCHEMBL7461492 | 0.65 | KMT2A (0.63) | SMN1; SMN2ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL8723486 | 0.64 | KMT2A (0.53) | ALDH1A1HSD17B10MAPTKMT2AKDM4E | |
| SCHEMBL27743103 | 0.64 | POLB (0.41) | ALDH1A1HSD17B10MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020049316-A1 | Protease inhibitors | HALBERT STACIE MARIE (US) | 2002-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049316-A1 | Protease inhibitors | CTSK, CTSZ, CTSG | SMN1; SMN2 4810/4885ALDH1A1 2831/4885HPGD 392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.