Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6455262 | 0.79 | CCNE1 (0.36) | CCNE1CDK2CDK5FFAR2 | |
| SCHEMBL24166406 | 0.63 | CCNE1 (0.36) | CCNE1CDK2CDK5FFAR2 | |
| SCHEMBL933968 | 0.59 | — | — | |
| SCHEMBL1808491 | 0.58 | ERCC5 (0.36) | — | |
| SCHEMBL6348870 | 0.56 | — | — | |
| SCHEMBL15896496 | 0.56 | TDP1 (0.40) | — | |
| SCHEMBL5034236 | 0.56 | CCNE1 (0.42) | CCNE1CDK2CDK5FFAR2 | |
| SCHEMBL13680962 | 0.54 | SLC6A3 (0.40) | — | |
| SCHEMBL22680069 | 0.54 | FFAR2 (0.35) | CCNE1CDK2CDK5FFAR2 | |
| SCHEMBL28202711 | 0.53 | ALDH1A1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308812-A2 | N-acylsulfonamide apoptosis promoters | Abbott Laboratories (US) | 2011-04-13 | — | — | EP | disclosed |