SCHEMBL15401905

SCHEMBL15401905

CNC(=O)C(O)c1ccccc1COc1ccccc1C(C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 1/20 0.47
KDM4E B2RXH2 4/20 0.47
ALDH1A1 P00352 4/20 0.47
GAA P10253 2/20 0.47
RXRA P19793 1/20 0.47
RXRB P28702 1/20 0.47
RXRG P48443 1/20 0.47
MAPT P10636 2/20 0.43
NPSR1 Q6W5P4 1/20 0.42
FABP4 P15090 1/20 0.40
FABP5 Q01469 1/20 0.40
ALOX15 P16050 1/20 0.39
RBP4 P02753 2/20 0.39
P2RY1 P47900 2/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
NISCH Q9Y2I1 1/20 0.38
TRPV1 Q8NER1 1/20 0.37
TP53 P04637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15401943 0.86 RXRA (0.48) NAMPTKDM4EALDH1A1GAARXRA
SCHEMBL15375377 0.86 FABP4 (0.54) NAMPTKDM4EALDH1A1GAARXRA
SCHEMBL15402006 0.86 NAMPT (0.46) NAMPTKDM4EALDH1A1GAARXRA
SCHEMBL15375564 0.85 RXRA (0.49) NAMPTKDM4EALDH1A1GAARXRA
SCHEMBL15402835 0.85 MAPT (0.44) KDM4EALDH1A1GAAMAPTNPSR1
SCHEMBL15402252 0.84 ALDH1A1 (0.47) KDM4EALDH1A1RXRARXRBRXRG
SCHEMBL15401423 0.84 LMNA (0.43) ALDH1A1FABP4FABP5NISCH
SCHEMBL15401870 0.81 POLB (0.44) KDM4EALDH1A1GAARXRARXRB
SCHEMBL15375495 0.79 MEN1 (0.44) KDM4EALDH1A1MAPTFABP4FABP5
SCHEMBL15402172 0.79 MAPT (0.43) ALDH1A1GAAMAPTNPSR1FABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2397459-B1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-12-16 EP disclosed
CN-103588657-A Method for producing phenylacetamide compound SUMITOMO CHEMICAL CO 2014-02-19 CN disclosed
US-8624062-B2 Method for producing phenylacetamide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-07 US disclosed
CN-102348677-A Method for producing phenylacetamide compound SUMITOMO CHEMICAL CO 2012-02-08 CN disclosed
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND MRPL21, AADAC, ARSA NAMPT 3909/4885KDM4E 2619/4885ALDH1A1 1164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.