SCHEMBL15401943

SCHEMBL15401943

COC(=O)C(O)c1ccccc1COc1ccccc1C(C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.48
RXRB P28702 1/20 0.48
RXRG P48443 1/20 0.48
NAMPT P43490 1/20 0.45
KDM4E B2RXH2 4/20 0.45
ALDH1A1 P00352 4/20 0.45
GAA P10253 2/20 0.45
MAPT P10636 2/20 0.44
NPSR1 Q6W5P4 1/20 0.43
FABP4 P15090 2/20 0.41
FABP5 Q01469 2/20 0.41
ALOX15 P16050 1/20 0.40
RBP4 P02753 2/20 0.39
MAPK1 P28482 1/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
NISCH Q9Y2I1 1/20 0.39
TP53 P04637 1/20 0.38
ITGA4 P13612 1/20 0.37
ITGB7 P26010 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15375377 0.87 FABP4 (0.54) RXRARXRBRXRGNAMPTKDM4E
SCHEMBL15401905 0.86 NAMPT (0.47) RXRARXRBRXRGNAMPTKDM4E
SCHEMBL15375564 0.86 RXRA (0.49) RXRARXRBRXRGNAMPTKDM4E
SCHEMBL15375381 0.84 MAPT (0.45) KDM4EALDH1A1GAAMAPTNPSR1
SCHEMBL15375470 0.83 RXRA (0.45) RXRARXRBRXRGKDM4EALDH1A1
SCHEMBL15401975 0.83 LMNA (0.43) ALDH1A1FABP4FABP5NISCH
SCHEMBL15402289 0.80 KMT2A (0.48) RXRARXRBKDM4EALDH1A1GAA
SCHEMBL15402006 0.80 NAMPT (0.46) RXRARXRBRXRGNAMPTKDM4E
SCHEMBL15375596 0.79 LTA4H (0.46) KDM4EALDH1A1MAPTFABP4FABP5
SCHEMBL15401546 0.79 MAPT (0.41) ALDH1A1GAAMAPTNPSR1FABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2682382-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-23 EP disclosed
US-8624062-B2 Method for producing phenylacetamide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-07 US disclosed
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND MRPL21, AADAC, ARSA RXRA 1438/4885RXRB 2062/4885RXRG 2362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.