Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.51 |
| ▸ | TMPRSS4 | Q9NRS4 | 11/20 | 0.50 |
| ▸ | P2RX1 | P51575 | 6/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 5/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | CHUK | O15111 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MYLK | Q15746 | 1/20 | 0.46 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15410865 | 0.90 | CYP11B2 (0.49) | TLR8TMPRSS4P2RX1P2RX4P2RX7 | |
| SCHEMBL15410528 | 0.84 | P2RX1 (0.45) | TLR8TMPRSS4P2RX1MEN1KDR | |
| SCHEMBL15410029 | 0.82 | RXFP1 (0.40) | TLR8MEN1KMT2A | |
| SCHEMBL15410721 | 0.81 | MEN1 (0.56) | TLR8MEN1KMT2A | |
| SCHEMBL15409614 | 0.81 | RAB9A (0.52) | MEN1KMT2AKCNMA1KDM4E | |
| SCHEMBL15411772 | 0.79 | TLR7 (0.38) | TLR8TMPRSS4MEN1KMT2A | |
| SCHEMBL15411818 | 0.79 | TLR8 (0.41) | TLR8TMPRSS4P2RX1MEN1KMT2A | |
| SCHEMBL15411037 | 0.79 | ABCC9 (0.52) | MEN1KMT2AKCNMA1GRM5 | |
| SCHEMBL15411820 | 0.78 | KDM4E (0.52) | MEN1KMT2AKDM4E | |
| SCHEMBL15411337 | 0.76 | NPC1 (0.53) | TMPRSS4MEN1KDRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140018566-A1 | PALLADIUM(II)-CATALYZED SELECTIVE FLUORINATION OF BENZOIC ACIDS AND DERIVATIVES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2014-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140018566-A1 | PALLADIUM(II)-CATALYZED SELECTIVE FLUORINATION OF BENZOIC ACIDS AND DERIVATIVES | AHR, DDT, AOC2 | TLR8 4122/4885TMPRSS4 4511/4885P2RX1 2449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.