Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15415551 | 0.73 | CRBN (0.49) | CRBNALDH1A1MAPTKMT2AALOX5 | |
| SCHEMBL12324357 | 0.69 | PLD1 (0.41) | GFERALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL2419530 | 0.69 | ALDH1A1 (0.60) | CRBNGFERALDH1A1MAPTDDB1 | |
| SCHEMBL29223441 | 0.68 | CRBN (0.43) | CRBNALDH1A1MAPTKMT2AALOX5 | |
| SCHEMBL7839621 | 0.68 | ROCK2 (0.37) | CRBNALDH1A1MAPTDDB1NPC1 | |
| SCHEMBL30702779 | 0.66 | CRBN (0.63) | CRBNALDH1A1KMT2AALOX5GSK3B | |
| SCHEMBL2198674 | 0.66 | CRBN (0.63) | CRBNALDH1A1KMT2AALOX5GSK3B | |
| SCHEMBL17596684 | 0.66 | ALDH1A1 (0.40) | GFERALDH1A1MAPTNPC1SMN1; SMN2 | |
| SCHEMBL29794136 | 0.66 | ALDH1A1 (0.40) | GFERALDH1A1MAPTNPC1SMN1; SMN2 | |
| SCHEMBL9372641 | 0.64 | ALDH1A1 (0.42) | CRBNALDH1A1MAPTDDB1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872508-A1 | IMIDAZOPYRIDINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB Biopharma SPRL (BE) | 2015-05-20 | — | — | EP | disclosed |
| WO-2014009295-A1 | IMIDAZOPYRIDINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB PHARMA S.A. (BE) | 2014-01-16 | — | — | WO | disclosed |