Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16235810 | 0.88 | PSEN1 (0.37) | TMEM97CCR2 | |
| SCHEMBL15416658 | 0.85 | ACLY (0.47) | CCR2 | |
| SCHEMBL16235731 | 0.82 | TDP1 (0.37) | CCR2 | |
| SCHEMBL15416636 | 0.82 | NUDT1 (0.40) | NUDT1BACE1 | |
| SCHEMBL23330647 | 0.81 | ACLY (0.41) | CCR2 | |
| SCHEMBL23301686 | 0.81 | CCR2 (0.55) | CCR2 | |
| SCHEMBL16235686 | 0.79 | ACLY (0.38) | — | |
| SCHEMBL15416457 | 0.79 | — | — | |
| SCHEMBL15685313 | 0.78 | TDP1 (0.41) | NUDT1BACE1CCR2 | |
| SCHEMBL16235887 | 0.78 | NUDT1 (0.40) | NUDT1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872502-A1 | NOVEL INDAZOLES FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | F. Hoffmann-La Roche AG (CH) | 2015-05-20 | — | — | EP | disclosed |
| WO-2014009302-A1 | NOVEL INDAZOLES FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2014-01-16 | — | — | WO | disclosed |