Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.48 |
| ▸ | APP | P05067 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA4 | P22748 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | APEX1 | P27695 | 2/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10339405 | 1.00 | LCK (0.48) | LCKAPPKDM4EHSD17B10CA2 | |
| SCHEMBL5464966 | 0.87 | MIF (0.44) | CA2CA4NFKB1CA12CA7 | |
| SCHEMBL15419981 | 0.86 | NFKB1 (0.50) | LCKAPPKDM4EHSD17B10CA2 | |
| SCHEMBL29065702 | 0.86 | NFKB1 (0.50) | LCKAPPKDM4EHSD17B10CA2 | |
| SCHEMBL5463214 | 0.84 | AKR1B1 (0.46) | LCKAPPKDM4EHSD17B10CA2 | |
| SCHEMBL26046327 | 0.81 | CA1 (0.49) | APPKDM4EHSD17B10CA2CA4 | |
| SCHEMBL28249242 | 0.80 | ESR1 (0.49) | APPKDM4EHSD17B10CA2CA4 | |
| SCHEMBL6668620 | 0.76 | ESR1 (0.48) | APPKDM4EHSD17B10CA2CA4 | |
| SCHEMBL6678566 | 0.76 | ESR1 (0.48) | APPKDM4EHSD17B10CA2CA4 | |
| SCHEMBL18900158 | 0.76 | CA1 (0.47) | APPKDM4EHSD17B10CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9089499-B2 | Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions | UNIVERSITE JOSEPH FOURIER-GRENOBLE 1 (FR) | 2015-07-28 | — | — | US | disclosed |
| US-20130272983-A1 | Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and their Use in Cosmetic or Dermatological Compositions | Universite Joseph Fourier-Grenoble 1. (FR) | 2013-10-17 | — | — | US | disclosed |
| US-20070183996-A1 | Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions | BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S. (FR) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070183996-A1 | Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions | TYR, CUTA, HPD | LCK 3991/4885APP 2180/4885KDM4E 1196/4885 |
| US-20130272983-A1 | Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and their Use in Cosmetic or Dermatological Compositions | TYR, CUTA, HPD | LCK 3991/4885APP 2180/4885KDM4E 1196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.